Results 71 to 80 of about 6,801,451 (249)

Global Tracer Facility Global Tracer Survey 2020 (Year 5) Survey Instrument Items [PDF]

, 2020
This survey instrument for the Year 5 Global Tracer Facility (GTF) Global Tracer Survey 2020 outlines the survey sections, area of focus, type of question and response options.
Australia Awards Global Tracer Facility
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Analysis of the influence of tunnel engineering on groundwater resources in karst mountain areas: A case study of a tunnel in Wushan county of Chongqing City

Carsologica Sinica
Tunnel construction can disrupt the groundwater balance, impacting the drainage of both surface water and groundwater, as well as causing other eco-environmental effects. This study takes a water-diversion tunnel as the research object.
Jinmei WEN, Tao WU, Xian LI, Chen JIANG, Li CHEN, Sheng LIU, Li MENG   +6 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Understanding Complex Hydraulic Heterogeneities in Crystalline Basement Aquifers Used as Drinking Water Sources

Geosciences
Managing groundwater flow in crystalline basement aquifers (CBAs) remains challenging due to their dependence on secondary permeability fields characterized by high spatial variability.
Kennedy O. Doro, Phebe I. Olabode, Margaret A. Adeniran, Michael A. Oladunjoye   +3 more
doaj   +1 more source

Simulation and interpretation of inter-well tracer tests

EPJ Web of Conferences, 2013
In inter-well tracer tests (IWTT), chemical compounds or radioactive isotopes are used to label injection water and gas to establish well connections and fluid patterns in petroleum reservoirs.
Dugstad Øyvind, Viig Sissel, Sagen Jan, Huseby Olaf   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Study on the structural characteristics of typical karst water systems in northwest Guangdong

Carsologica Sinica
Karst water systems formed by carbonate dissolution comprise a complex multi-medium framework of pores, fractures, caves, and conduits. They are not only the principal reservoirs and conduits of groundwater supply, but are also closely linked to ...
Shiliang TU, Zhuohan ZHUANG, Zhuobin LIN, Shoujun JIANG, Xing GONG   +4 more
doaj   +1 more source

Effects of the vadose zone on groundwater flow and solute transport characteristics in mountainous karst aquifers – the case of the Javorniki–Snežnik massif (SW Slovenia)

Acta Carsologica, 2018
Tracer tests are rarely applied in mountainous karst aquifers due to difficult or limited basic data acquisition, problems of access and expected strong tailing effects in tracer breakthrough.
Metka Petrič, Janja Kogovšek, Nataša Ravbar   +2 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source