Results 61 to 70 of about 6,801,451 (249)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Tracer test of reinjection into a metamorphic rock geothermal reservoir in Xishan area, Taiyuan City
Shuiwen dizhi gongcheng dizhiThe geothermal resources hosted in metamorphic rock in Hekou Town, Xishan area, Taiyuan City, are characterized as a medium-low temperature, mountain-type geothermal field, with geothermal water temperature of 40–42 ℃, and the hydrochemical type of Cl ...
Xiaoyu YUAN
doaj +1 more source
Temporal moments of a tracer pulse in a perfectly parallel flow system [PDF]
, 2002 Perfectly parallel groundwater transport models partition water flow into isolated one-dimensional stream tubes which maintain total spatial correlation of all properties in the direction of flow.
W. E. Bardsley, Bardsley, W. Earl
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Global Tracer Facility Longitudinal Global Tracer Survey 2021 (Year 6) - Survey Instrument [PDF]
, 2021 This survey instrument for the Year 6 Global Tracer Facility (GTF) Global Tracer Survey 2021 outlines the survey sections, area of focus, type of question and response options.
Australia Awards Global Tracer Facility
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A test of the effect of boundary conditions on the use of tracers in reservoir characterization [PDF]
Geofísica Internacional, 2009 Tracer tests are fundamental in characterizing fluid flow in underground formations. However, the setting of appropriate boundary conditions in even simple analytical models has historically been controversial, mainly due to the lack of sufficient ...
C. Somaruga +3 more
doaj
TRAC, a collaborative computer tool for tracer-test interpretation
EPJ Web of Conferences, 2013 Artificial tracer tests are widely used by consulting engineers for demonstrating water circulation, proving the existence of leakage, or estimating groundwater velocity. However, the interpretation of such tests is often very basic, with the result that
Fécamp C. +10 more
doaj +1 more source