Results 81 to 90 of about 170,529 (304)

Penetran Tracheal Injury: A Rakshe Accident

, 2019
Tracheal injury is a rare pathology, but 30% of all cases can be fatal and 50% of those patients will deteriorate in couple of hours and may lead to death.
Mehmet Yavuz Zıraman, Hüseyin Fatih Sezer, Hakan Dayanır, DAYANIR, HAKAN, SEZER, HÜSEYİN FATİH, ZIRAMAN, MEHMET YAVUZ   +5 more
core   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

Advanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin, Ping Zhang, Qing Song, Tao Li, Yuqin Zeng, Ping Chen   +5 more
wiley   +1 more source

Tracheal Bridge for Reconstruction of the Upper Airway in Double Tracheal Stenosis

, 2020
Tracheal reconstruction is a complex surgical procedure that requires a well-trained, multidisciplinary team to achieve optimal results. No reviews or case reports involving the use of a healthy tracheal bridge to achieve reconstruction after extensive ...
García-Herreros L.G., Santivañez J.J., Granada J., Díaz A., Granada, Julio, Díaz, Angela, García-Herreros, Luis Gerardo, Santiváñez, Juan José   +7 more
core   +2 more sources

Tracheoechography versus CT tracheography for assessment of idiopathic pulmonary fibrosis related tracheopathy

Egyptian Journal of Chest Disease and Tuberculosis, 2015
Background: Idiopathic pulmonary fibrosis (IPF) is a specific type of chronic, progressive interstitial pneumonia with fibrosing nature of tracheobronchial tree.
A.M. Abumossalam, M.M. Elshafeey, E.M. Abdelsalam   +2 more
doaj   +1 more source

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

Advanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang, Qilan Li, Hao Liu, Xuehui Gao, Hongyu Nie, Lang Chen, Mei He, Xuefeng Li, Xiangming Fang, Jiqian Xu, Hao Zhang, Jiahong Xia, You Shang   +12 more
wiley   +1 more source

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

Advanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu, Siyu Wang, Tong Lin, Jingyi Zhang, Jingya Yang, Dixiang Kang, Wenting Zhao, Na Yu, Meimei Wang   +8 more
wiley   +1 more source

Ischemic Postconditioning Protects Aged Myocardium Against Ischemia/Reperfusion Injury by Regulating Mitochondrial Dynamics via piR‐4913

Advanced Science, EarlyView.
A tiny RNA tips the scales of cardiac injury in aging. piR‐4913 recruits OGT to Drp1 and drives its O‐GlcNAcylation at Thr604, promoting excessive mitochondrial fission that aggravates ischemia‐reperfusion injury. Ischemic postconditioning silences this pathway to restore mitochondrial balance and protect the aged myocardium, revealing piR‐4913 as a ...
Xiangyu Zhao, Yanchun Li, Nan Li, Juan Zhang, Xiaolong Ma, Fei Yang, Ruihan Long, Yining Tian, Yichen Wang, Shengchao Ma, Huiping Zhang, Yideng Jiang   +11 more
wiley   +1 more source

A Tracheal Perivascular Epithelioid Cell Tumor in a 17‐Year‐Old Male

Clinical Case Reports
This case is the second to report a patient with a tracheal perivascular epithelioid cell tumor (PEComa), who previously underwent multiple intratracheal CO2 cryotherapy treatments.
Yali Gao, Lipeng Zhang, Shaojun Bo, Xianfa Xu   +3 more
doaj   +1 more source

Anesthetic Management of Penetrating Tracheal Injury in a 3-Year-Old Child: A Case Report

Annals of Cardiac Anaesthesia
Penetrating tracheal injuries in children are uncommon and present significant diagnostic and airway challenges. We report the case of a 3-year-old boy who sustained an accidental penetrating neck trauma and was taken up for tracheal repair.
Malik Indira, Ahlawat Geeta, K. Teja Mallela Venkata, Dalai Manasmita, Gupta Disha, Chandra Prakash   +5 more
doaj   +1 more source

Tracheal tissue regeneration

, 2011
Tracheal circumferential defects involving more than half of the tracheal wall still represent an unsolved problem. Several studies have developed different methods to help repair cartilage and improve healing but a suitable tracheal reconstruction or ...
F. Acocella, S. Brizzola
core   +1 more source