Results 231 to 240 of about 98,836 (311)

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Peri‐operative fasting in adults: an international, multidisciplinary consensus statement

Anaesthesia, EarlyView.
Summary Introduction Evidence suggests that existing pre‐operative fasting guidelines are associated with prolonged fasting times. Prolonged fasting, particularly from clear liquids, has the potential to harm patients through reduced peri‐operative wellbeing; impaired glucose metabolism and peri‐operative inflammatory response; delayed return of bowel ...
Anne Rüggeberg, Kariem El‐Boghdadly, Federico Bilotta, Marta Dias Vaz, Anne Marie Camilleri Podesta, Ib Jammer, Ehrenfried Schindler, Jamie Elmawieh, Alexander Nagrebetsky, Stakeholders, Christiane Beck, Maximilian Heinz Beck, David Borshoff, Lionel Bouvet, Madjid Boukantar, David Bunting, Sharon Carey, Mirka Cikkelova, Matthew Checketts, Michael Clarius, Aaron Conway, Marc Coppens, Rafaela Coutinho, Arianna Dal Buono, Pradeep A Dongare, Richard Dutton, Dilay Erbaş, David Ferreira, Adriano Friganovic, Peter Frykholm, Adrian W Gelb, Andrew M Goldsweig, Steven Green, Steven Greenberg, Jana G Hashash, Helen Haskell, Arvid Steinar Haugen, Dorthe Hjort Jakobson, Erin Hommel, Ryan Howle, Jaime Hyman, Mohua Jain, Girish P Joshi, Noelleen Kiprillis, Inci Kirtil, Shanu Kothari, Peter Kranke, Dileep N Lobo, Benjamin Loveday, Michael Margarson, Phuong Markman, Marije Marsman, Carmen Mazilu, Viorica Nedelcu, Anahi Perlas, Susanna Price, Finn Radtke, Kate Rivett, Michael Sander, Faiz Shariff, Aistė Štaraitė, Pietro Paolo Tamborrino, Panagiota Tsikala, Arnaldo Valedon, Harm HJ Van Noort, Matthew Wiles, Meryem Yilmaz, Marko Zdravkovic   +67 more
wiley   +1 more source

Risk factors for perioperative respiratory adverse events and unplanned intensive care admission in children with juvenile-onset recurrent respiratory papillomatosis undergoing carbon dioxide laser resection. [PDF]

World J Pediatr Surg
Yang X, Xu D, Zhan R, Lu Y.
europepmc   +1 more source

Peri‐operative management of diabetes mellitus: a multidisciplinary consensus statement from the Association of Anaesthetists and the Joint British Diabetes Societies for Inpatient Care group

Anaesthesia, EarlyView.
Summary Introduction Surgery in patients with diabetes mellitus is associated with increased morbidity and mortality compared with those who do not have diabetes mellitus. This is likely multifactorial and could be attributed to organisational issues; dysglycaemia; hospital‐acquired diabetic ketoacidosis; errors with insulin prescribing and ...
Nicholas A. Levy, Kariem El‐Boghdadly, Dileep N. Lobo, Daniel J. Stubbs, Parizad Avari, Donal Buggy, Claire Frank, Kim Howson, Jinty Moffett, Emma Morris, Omar G. Mustafa, Glynn Nash, Pádraig Ó Scanaill, Sarah Procter, Gerry Rayman, Kim Russon, Caroline Thomas, Sarah Tinsley, Allan Xu, Ketan Dhatariya   +19 more
wiley   +1 more source

Pathogenicity and Bioinformatics Analysis of Two GI-13 Infectious Bronchitis Virus Strains in China. [PDF]

Transbound Emerg Dis
Jin J, Zhao L, Lv Y, Bao E.
europepmc   +1 more source

Critical care delirium: prevention, identification and management: a narrative review

Anaesthesia, EarlyView.
Summary Introduction Delirium is a frequent complication of critical illness and remains an important cause of short‐ and long‐term morbidity for patients admitted to ICUs. Delirium is associated with prolonged mechanical ventilation; extended ICU and hospital stay; and longer‐term health issues. Development is associated with patient (e.g.
Stephanie Kieswick, Ben Gibbison
wiley   +1 more source

Identification of <i>Drosophila melanogaster</i> as a model organism in COPD research. [PDF]

Front Immunol
Zhang Y, Kou J, Zhang Y, Huang H, Yang Y, Liu C, Lu T, Zhao X, Liu Y, He J.   +9 more
europepmc   +1 more source

Multinodular Goiter: Diagnosis and Management [PDF]

, 1994
Lazarus, J. H., Pickardt, C. R., Scriba, Peter Christian, Wheeler, Malcolm H.   +3 more
core  

Microtubule Inner Protein CFAP77 Contributes to Sperm Motility and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background Sperm motility is essential for male fertility, and its regulation is dependent on the structural integrity of the axoneme. The axoneme consists of a conserved “9+2” microtubule arrangement and is supported by microtubule inner proteins. However, the functional significance of many microtubule inner proteins remains unclear.
Haoting Wang, Anh Hoang Pham, Mengjiao Luo, Masahito Ikawa, Haruhiko Miyata   +4 more
wiley   +1 more source

A warning of a rare complication-delayed tracheal rupture after thyroidectomy: a report of three cases. [PDF]

Gland Surg
Jiang Y, Hu L, Zhao X, Gong H, Yang Y, Jiang T, Su A.   +6 more
europepmc   +1 more source