Results 71 to 80 of about 1,309,938 (248)

Super-fiber tracked robot VAMOS (Development and experimental evaluation of super-fiber track)

open access: yesNihon Kikai Gakkai ronbunshu, 2019
In this study, we develop a new track having a belt made of a fiber and experimentally evaluate its traveling performance. The developed track has a belt made of a high strength and high modulus super fiber.
Masataku SUTOH, Kotaro SHIMIZU
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Groundwater in Germany: challenges, solutions, and the BMBF funding measure LURCH: sustainable groundwater management

open access: yesEnvironmental Sciences Europe
Water is fundamental to life and a vital element for sustainable development. In Germany, groundwater systems are increasingly facing challenges due to climate change and competing demands from various sectors, including drinking water supply ...
Sarah Fieger, Thomas Track
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Dual Track Liberalization: With and Without Losers [PDF]

open access: yes
The success of the Chinese economic reforms has been linked by many observers to the implementation of a dual track liberalization mechanism. This approach, relying upon the continued enforcement of existing contracts and the simultaneous creation of a ...
Jiahua Che, Giovanni Facchini
core   +4 more sources

Vertical Interaction Between a Driving Wheelset and Track in the Presence of the Rolling Surfaces Harmonic Irregularities

open access: yesRomanian Journal of Transport Infrastructure, 2020
The driving wheelset is used in railway traction (locomotives, electric trains, trams, etc.) to support part of the weight of the suspended mass and to drive and brake the vehicle.
Mazilu Traian   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Research on wheel/rail coupled vibration of metro cars

open access: yes机车电传动, 2022
The wheel/rail coupled vibration modal is an inherent property of the wheel/rail system, and mastering the coupling vibration characteristics between wheel and rail is inevitable and practical to reduce wheel out of round wear and rail corrugation.
ZHOU Zuobin, WU Xingwen, CHI Maoru
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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