Results 81 to 90 of about 3,845,343 (295)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Making hurricane track data accessible [PDF]

open access: yes, 2010
Our interactive tool allows the exploration, validation and presentation of hundreds of years of dynamically simulated storm tracks. The tracks were generated as part of a research project to improve the risk assessment of tropical storm damage by the ...
Dykes, J.   +4 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Fast Track, Bush Track

open access: yesAustralian and International Journal of Rural Education, 2014
Previous research related to this study explored early career female leaders’ experiences in rural school settings, and probed the personal and professional challenges they faced and their motivations to accept formal and informal leadership roles ahead of the usual timeframes (e.g., Graham, Miller & Paterson, 2009).
Judith Miller   +2 more
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The nature of the Island and Banana States in Atoll sources and a Unified Model for Low Mass X-ray Binaries

open access: yes, 2013
We propose an explanation of the Island and Banana states and the relation between Atoll and Z-track sources, constituting a unified model for Low Mass X-ray Binaries (LMXB).
Balucinska-Church, M.   +2 more
core   +1 more source

Super-fiber tracked robot VAMOS (Development and experimental evaluation of super-fiber track)

open access: yesNihon Kikai Gakkai ronbunshu, 2019
In this study, we develop a new track having a belt made of a fiber and experimentally evaluate its traveling performance. The developed track has a belt made of a high strength and high modulus super fiber.
Masataku SUTOH, Kotaro SHIMIZU
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Trade Promotion Authority (TPA)/Fast-Track Renewal: Labor Issues [PDF]

open access: yes, 2007
[Excerpt] This report examines issues relating to TPA/fast-track labor provisions in the larger context of global labor issues. It: (1) identifies the players and their positions; (2) tracks the enforceable labor provisions in TPA/fast-track laws and the
Bolle, Mary Jane
core   +1 more source

The Timing Properties of Sco X-1 along its Z track as seen with EXOSAT

open access: yes, 1999
We present a systematic, homogeneous analysis of all the EXOSAT ME, high time resolution data on Sco X-1. We investigate all power spectral properties of the $
Dieters, Stefan W.   +1 more
core   +1 more source

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