Results 41 to 50 of about 1,446,410 (276)

Geometry-aware manipulability learning, tracking, and transfer [PDF]

open access: yesThe International Journal of Robotics Research, 2020
Body posture influences human and robot performance in manipulation tasks, as appropriate poses facilitate motion or the exertion of force along different axes. In robotics, manipulability ellipsoids arise as a powerful descriptor to analyze, control, and design the robot dexterity as a function of the articulatory joint configuration.
Noémie Jaquier   +3 more
openaire   +6 more sources

Detecting Embankment Instability Using Measurable Track Geometry Data

open access: yesInfrastructures, 2020
The British railway system is the oldest in the world. Most railway embankments are aged around 150 years old and the percentage of disruption reports that feature them is frequently higher than other types of railway infrastructure.
David Kite, Giulia Siino, Matthew Audley
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Modeling the track geometry variability [PDF]

open access: yes, 2012
International audienceAt its building, the theoretical new railway line is supposed to be made of perfect straight lines and curves. This track geometry is however gradually damaged and regularly subjected to maintenance operations. The analysis of these
Duhamel, Denis   +3 more
core   +4 more sources

Comparison of methods for evaluation of the track geometry quality

open access: yesActa Polytechnica CTU Proceedings
This paper is aimed at evaluation of the track geometry quality based on data from a measuring car for railway superstructure. The evaluation of the track geometry quality serves as a necessary basis for effective track maintenance planning.
Erik Dušek, Richard Svoboda
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Optimisation of railway tamping scheduling

open access: yesHeliyon
This research was devoted to optimising opportunistic tamping scheduling to present a cost-effective approach that considers both preventive and corrective tamping activities.
Mahdi Khosravi   +3 more
doaj   +1 more source

A method for geometric features equivalence to assess the thermal behavior in the selective laser melting process

open access: yesJournal of Materials Research and Technology, 2023
Selective laser melting (SLM) is a common technique categorized as one of the metal Additive Manufacturing (AM) processes to efficiently manufacture complex geometries.
Zhiqiang Yan   +7 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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