Results 91 to 100 of about 604,637 (265)

On the effective number of tracked trajectories in amblyopic human vision

Journal of Vision, 2008
We estimated the effective number of trajectories that amblyopic observers could track with their amblyopic eyes and their non-amblyopic eyes using stimuli and methods described in S. P. Tripathy, S. Narasimhan, and B. T. Barrett (2007). The stimuli consisted of dots moving along straight-line trajectories.
Srimant P, Tripathy, Dennis M, Levi
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Bivariate normal distribution for finding inliers in Hough space for a Time Projection Chamber

EPJ Web of Conferences, 2017
A Time Projection Chamber (TPC) is foreseen as the main tracking detector for the International Large Detector (ILD), one of the two detectors for the next candidate collider named International Linear Collider (ILC) [1].
Noori Shirazi Amir, Fleck Ivor
doaj   +1 more source

Adaptive Hough Transform for Charged Particles Tracking at the LHC [PDF]

EPJ Web of Conferences
The High-Luminosity Large Hadron Collider (HL-LHC) will significantly increase the number of simultaneous proton-proton interactions per bunch crossing, making efficient track reconstruction increasingly challenging.
Bold Tomasz, Horodenski Stefan, Libucha Piotr   +2 more
doaj   +1 more source

Slice and Gordian numbers of track knots

Osaka Journal of Mathematics, 2005
We present a class of knots associated with labelled generic immersions of intervals into the plane and compute their Gordian numbers and 4-dimensional invariants. At least 10% of the knots in Rolfsen's table belong to this class of knots. We call them track knots. They are contained in the class of quasipositive knots.
openaire   +5 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Research on multi-stage on-board detection algorithm of track defects of high-speed railway based on the influence mechanism of track defects

Scientific Reports
The ballastless track defects, such as rail corrugation, fastener looseness, and CA mortar layer disengagement, will affect the safety of high-speed train operation.
Jianbo Li, Hongmei Shi, Ji Qiu, Jiaqi Shi, Zujun Yu, Zengqiang Jiang   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source