Results 71 to 80 of about 604,637 (265)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Determination of the work scope for removal of speed restrictions related to the track plan
Nauka ta progres transportu, 2012 The greatest number of restrictions is related to the parameters and condition of curvilinear track sections. The technique for determination of cost of reorganization of curves at introduction of high-speed traffic for difficult sections of the track ...
I.P. Korzhenevich +2 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Crack-Configuration Analysis of Metal Conductive Track Embedded in Stretchable Elastomer
Micromachines, 2018 This paper reports the analysis of the crack configuration of a stretched metal conductive track that is embedded in a stretchable elastomer. The factor determining the crack configurations is analyzed by modeling as well as experiments.
Tomoya Koshi, Eiji Iwase
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
An Adaptive Density-Based Fuzzy Clustering Track Association for Distributed Tracking System
IEEE Access, 2019 The problem of duplicate track determination called “Track-to-Track association” occurs when a target is reported by different sensors, and it is regarded as one of the most important challenges in distributed multi-sensor tracking systems.
Mousa Nazari +2 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Development of a low-cost senor based aid for visually impaired people
Current Directions in Biomedical Engineering, 2016 The aim of the project is the development of an aid for blind or visually impaired people, considering economic aspects as well as easy adaptability to various daily situations.
Loepthien Nora +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Mission Planning and Trajectory Optimization in UAV Swarm for Track Deception against Radar Network
Remote SensingIn this article, a mission planning and trajectory optimization scheme in unmanned aerial vehicle (UAV) swarm for track deception against radar networks is proposed.
Yihan Li +3 more
doaj +1 more source