Results 31 to 40 of about 10,206 (280)

Vaccinations and Vaccinators’ Tracking System in Island Settlements: CHAD 2017-2018 [PDF]

Journal of Immunological Sciences, 2021
Introduction: Chad is a country within the Lake Chad sub region, currently at risk for poliovirus infection. The Lake Chad Task Team on polio eradication in this sub region made significant efforts to reduce the risk of polio transmission in Chad by tacking immunization teams in the Island Settlement using a Geographic Information System (GIS ...
Atagbaza, Ajiri, Okeibunor, Joseph, Amadou, Felix, Kalilou, Souley, Esanga, Aime Matela, Bagayoko, Adama Nanko, Bohoussou, Philbert, Igweonu, Obianuju, Seid, Mahamat Mbodou, Aliyu, Ahmad Jibril, Ntezayabo, Elizabeth Benoit, Traore, Mohamed Alimou, Nzioki, Mwanza, Olaleye, Adebola, Aluma, Adele Daleke Lisi, Sedick, Djibrine Abakar, Seid, Adam Mahamat, Tahir, Mahamat Saleh, de Medeiros, Narcisse, Rabenarivo, Bakoly, Diomande, Fabien, Mkanda, Pascal   +21 more
openaire   +2 more sources

Image-Aided Analysis of Ballast Particle Movement Along a High-Speed Railway

Engineering, 2023
As a core infrastructure of high-speed railways, ballast layers constituted by graded crushed stones feature noteworthy particle movement compared with normal railways, which may cause excessive settlement and have detrimental effects on train operation.
Xuecheng Bian, Wenqing Cai, Zheng Luo, Chuang Zhao, Yunmin Chen   +4 more
doaj   +1 more source

The Influence of Subgrade Subsidence on Train Track Dynamic Interaction

, 2012
Railways 2012 The First International Conference on Railway Technology: Research, Development and Maintenance Las Palmas de Gran Canaria, Spain 18-20 April 2012This paper reports results from a numerical model to calculate subgrade settlement in ...
E.J. OBrien, O'Brien, Eugene J., Gavin, Kenneth, A. Taheri, Taheri, A., K. Gavin   +5 more
core   +1 more source

The interaction between railway vehicle dynamics and track lateral alignment

, 2016
Track geometry deteriorates with traffic flow, thus it needs to be regularly restored using tamping or other method. As the deterioration is mainly in the vertical direction this aspect has been widely studied and models for its analysis developed ...
Gong, Cencen, Iwnicki, Simon, Bezin, Yann   +2 more
core   +1 more source

Effect of Sleeper Size on Ballasted Track Settlement

Quarterly Report of RTRI, 2004
This paper discusses the effect of sleeper size on the cyclic deformation properties of railway ballast under cyclic loading. A series of full-scale cyclic loading tests were performed using sleepers of different lengths and heights, from which it is discovered that the sleeper support setup is basically a center support for 2.0m-long and supports at ...
NAMURA, Akira, KOHATA, Yukihiro, MIURA, Seiichi   +2 more
openaire   +2 more sources

Dynamic Wheel-Rail Force-Based Track-Irregularity Evaluation for Ballasted Track on Serviced Railway by Adjacent Excavation

Applied Sciences, 2021
This study investigates a load-based, track-irregularity-analysis technique for ballasted tracks on a serviced railway line with respect to excavation work conducted in adjacent sites.
Jung-Youl Choi, Dong-Ryong Park, Jee-Seung Chung, Sun-Hee Kim   +3 more
doaj   +1 more source

Settlement behaviour of hybrid asphalt-ballast railway tracks [PDF]

Construction and Building Materials, 2019
The use of structural asphalt layers inside ballasted railway tracks is attractive because it can increase track bending stiffness. Therefore, for the first time, this paper investigates the long-term settlement characteristics of asphaltic track in the presence of a subgrade stiffness transition zone.
Yu Z, Connolly DP, Woodward PK, Laghrouche O   +3 more
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source