Results 61 to 70 of about 3,239,156 (327)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Reducing attrition in panel studies in developing countries.
, 2004 BACKGROUND: Panel studies offer repeated observations of individuals over time, but the mobility of populations in the developing world often causes attrition in panel studies.
Hill, Zelee
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
RLita: A Region-Level Image–Text Alignment Method for Remote Sensing Foundation Model
Remote SensingThe foundation model fine-tuning optimization method has gradually become a research hotspot due to the development of generative pretrained transformer. However, compared to natural scene images, remote sensing images have a wide range of spatial scales,
Qiang Zhang, Decheng Wang, Xiao Yu
doaj +1 more source
Multiplexing modulation design optimization and quality evaluation of BDS-3 PPP service signal
Satellite Navigation, 2022 The Precise Point Positioning (PPP) service of BeiDou-3 Navigation Satellite System (BDS-3) is implemented on its Geostationary Earth Orbit (GEO) satellites.
Cheng Liu +7 more
doaj +1 more source
Fish tracking technology development. Phase 1 project definition desk study [PDF]
, 1994 The document reports on Phase 1 of a definition study to appraise the options to develop fish tracking equipment, in particular tags and data logging systems in order to improve the efficiency of the Environment Agency's tracking studies and to obtain a ...
Moore, A, Potter, E.C.E.
core
, 2014 The limiting magnitude is a key issue for optical interferometry. Pairwise fringe trackers based on the integrated optics concepts used for example in GRAVITY seem limited to about K=10.5 with the 8m Unit Telescopes of the VLTI, and there is a general ...
Benkhaldoum, Zouhair +8 more
core +1 more source