Results 91 to 100 of about 8,633,591 (312)

Strain-level dynamics of Akkermansia muciniphila in the human gut microbiota

open access: yesAMB Express
Akkermansia muciniphila (Akk), a mucin-degrading bacterium residing in the human gut, plays a pivotal role in intestinal health. This study investigated its temporal dynamics, strain-level diversity, and cross-regional transmission using longitudinal ...
Na Han   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Path-tracking control of bevel-tip needles using Model Predictive Control

open access: yes, 2016
The bevel-tip flexible needle is an improvement of the clinical puncture needle and has the potential to reduce surgery traumas and improve puncture accuracy.
Xu WL(徐卫良)   +3 more
core  

Robust tracking control for the yaw control of helicopter with time-varying uncertainty

open access: yes, 2007
This paper deals with the problem of robust tracking control with adaptation mechanism. A linear time-invariant system with time-varying ellipsoidal uncertainty is considered.
Zhao XG(赵新刚)   +3 more
core   +1 more source

Unveiling the Mutations and Conservation of InlA in Listeria monocytogenes

open access: yesMicroorganisms
Listeria monocytogenes (L. monocytogenes) is a pathogen that is transmitted through contaminated food and causes the illness known as listeriosis. The virulence factor InlA plays a crucial role in the invasion of L.
Lingling Li   +8 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Sampling rate tracking control of networked control systems based on cognitive knowledge of packet disordering

open access: yes, 2013
This paper focuses on the sampling rate tracking control of networked control systems (NCSs) with packet disordering. In view of the coupled relation between packet disordering and sampling rate, a novel sampling rate control algorithm, referring to the ...
Li JN(李金娜)   +5 more
core  

Event-Triggered Tracking Control of Networked and Quantized Control Systems

open access: yes, 2021
This paper studies the tracking control problem of networked and quantized control systems under both multiple networks and event-triggered mechanisms.
Ren, Wei,   +5 more
core   +1 more source

The global epidemiology, risk factors, and mortality prediction of nocardiosis: an easily missed opportunistic infection

open access: yesScientific Reports
This study was to comprehensively investigate the epidemiology of nocardiosis worldwide and develop an interpretable machine learning (ML) model to predict mortality in patients with nocardiosis.
Bingqian Du   +10 more
doaj   +1 more source

Quorum sensing regulators AphA and HapR differentially regulate fluvibactin biosynthesis in Vibrio fluvialis

open access: yesFrontiers in Microbiology
IntroductionSiderophores are secondary metabolites with high affinity and specificity for iron and play a crucial role in iron acquisition. Vibrio fluvialis, an emerging foodborne opportunistic pathogen of increasing concern, produces the catechol ...
Qian Cheng   +9 more
doaj   +1 more source

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