Results 101 to 110 of about 8,633,591 (312)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Extended Markov Tracking with an Application to Control

, 2004
We present here a tracking method for Markovian system dynamics which operates in an on-line fashion, during interaction with the system. Existence of a simple numerical solution of the technique is demonstrated.
Rabinovich, Zinovi, Rosenschein, Jeffrey S., Zinovi Rabinovich, Jeffrey S. Rosenschein   +3 more
core  

Evaluation of the cross-immunity between Mycobacterium tuberculosis and Mycobacterium abscessus in vitro

BMC Microbiology
Mycobacterium tuberculosis (M. tuberculosis) and Mycobacterium abscessus (M. abscessus) are important pathogens that can cause lung diseases. Given the abundance of shared antigens between these two pathogens, evaluating the cross-immunization between ...
Da Xu, Yujie Gu, Guilian Li, Ruihuan Wang, Shiqi Xiao, Hongyang Duan, Jingwei Jiang, Xiuqin Zhao, Kanglin Wan, Xinyue He, Haican Liu, Yongliang Lou   +11 more
doaj   +1 more source

Study of the relationships among known virulence genes, coccoid transformation and cytotoxicity of Helicobacter pylori in different clinical diseases

Virulence
Background Helicobacter pylori (H. pylori) has infected approximately 4.4 billion individuals worldwide. The known virulence genes and the existing H. pylori typing methods have not been shown to have a recognized correlation with its infectivity.
Yao Xiao, Binghua Zhang, Huifang Zhang, Zehui Zhang, Fanliang Meng, Xin Zhao, Jianzhong Zhang, Di Xiao   +7 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Tracking of secondary and temporary objects in structural concrete work [PDF]

, 2014
Purpose - Previous research has shown that "Scan-vs-BIM" object recognition systems, that fuse 3D point clouds from Terrestrial Laser Scanning (TLS) or digital photogrammetry with 4D project BIM models, provide valuable information for tracking ...
Yelda Turkan, Haas, Carl T., Bosché, Frédéric, Frédéric Bosché, Carl T. Haas, Turkan, Yelda, Ralph Haas, Haas, Ralph   +7 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A retrospective study revealing complex viral diversity and a substantial burden of HPV infection in SARS-CoV-2 positive individuals, Sierra Leone

Virology Journal
Background The COVID-19 pandemic has underscored the critical role of sequencing technology in disease control and outbreak response. However, resource limitations and challenging environments often impede such efforts in low and middle-income countries.
Xiaozhou He, Alie Brima Tia, Qikai Yin, Liping Gao, Lili Wang, Tingting Tian, Kang Xiao, Yi Zhang, Fengyu Tian, Xuejun Ma, Doris Harding, Xiaoping Dong   +11 more
doaj   +1 more source

Cell surface Toll-like receptor polymorphisms influence Bartonella and ectoparasite infections in striped hamsters

iScience
Summary: This study explored how polymorphisms in cell surface Toll-like receptors (TLRs) influence susceptibility to Bartonella and ectoparasite infections in striped hamsters.
Xinchang Lun, Yujuan Yue, Yiguan Wang, Guichang Li, Ning Zhao, Fengxia Meng, Qiyong Liu, Pengbo Liu, Zihao Wang, Zhenxu Wang, Xiuping Song, Jun Wang, Ying Liang, Liang Lu   +13 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source