Results 191 to 200 of about 212,052 (223)

Microgel‐Based Immunomodulatory Biomaterials for Regulating Macrophage Polarization

Journal of Biomedical Materials Research Part A, Volume 114, Issue 8, August 2026.
Macrophages are key regulators of the immune system. Modulating their phenotype from pro‐inflammatory (M1) to pro‐regenerative (M2) is key to engineering implantable tissue scaffolds for regenerative medicine. Understanding the cell‐matrix mechanosensitive trends macrophages exhibit with microgel‐based biomaterials will enhance future research.
Cody Tuftee, Muhammad Rizwan
wiley   +1 more source

Effect of SBS Copolymer Molecular Structure on the Long‐Term Aging and Resilience of Asphalt Binders: A Multiscale Morphological Study

Macromolecular Materials and Engineering, Volume 311, Issue 8, August 2026.
Vinyl content governs the long‐term ageing resistance of SBS‐modified bitumen. Multiscale AFM, FM, SEM, and FTIR analyses show that low‐vinyl SBS copolymers (L‐SBS, B‐SBS) undergo pronounced bee‐phase growth, stiffening, and network fragmentation after PAV ageing, whereas high‐vinyl variants (HV‐SBS, DB‐SB) retain their morphology and chemistry ...
Sk Sohel Islam, Ayana Ghosh, Bhupendra Singh, Gondaimei Rongmei Naga Ransinchung, Sham S. Ravindranath, Praveenkumar Thaloor Ramesh, Zelalem Mebrate   +6 more
wiley   +1 more source

Targeting Melanoma‐Specific Tyrosinase Disrupts Cytoskeleton Dynamics for Precision Apoptosis Induction by a De Novo Designed Cyclic Peptide

MedComm, Volume 7, Issue 8, August 2026.
This study develops a tyrosinase‐activated cyclic peptide self‐assembly system to combat drug‐resistant melanoma. Cyclization of tyrosine/lysine‐rich peptides via ortho‐phthalaldehyde enables tyrosinase‐triggered quinone formation and nanostructure assembly, disrupting melanoma cell cytoskeletons by blocking actin polymerization and inducing apoptosis.
Ruoyang Zhao, Xiaowei Wang, Jiajia Hu, Yonghan Zhang, Xinmin Zhao, Qianqian Hu, Yajin Wen, Yuxin Jiao, Huabin Zhu, Fan Yang, Qingqing Sun, Jun Guo, Feng Zhang, Min Wu   +13 more
wiley   +1 more source

Mechanically Regulated Nanozymes for Remote Metabolic Reprogramming and Precise Cancer Therapy

Angewandte Chemie, Volume 138, Issue 30, 20 July 2026.
Inspired by mechanoenzymes, a ferrocene‐based mechanically regulated nanozyme converts acoustic shear force into enhanced peroxidase‐like activity by decreasing electron density and alleviating steric hindrance at the Fe active sites, thereby rewiring redox homeostasis. Leveraging this remote regulatory mechanism, a multienzyme‐regulated nanoreactor is
Fangman Chen, Xiaochun Xie, Hanyao Huang, Ka Hong Wong, Jiying Liu, Hui Fang, Shaowen Wang, Jianfang Cao, Yu Tao, Mingqiang Li, Chao Yang, Wen Sun, Dan Shao, Yunlu Dai   +13 more
wiley   +2 more sources

Unilateral ductus deferens aplasia with terminal cystic dilation in a Bernese mountain dog

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract An incidental caudal abdominal mass was discovered in a 5‐year‐old, male, entire Bernese mountain dog. Investigations showed a terminal cystic dilation of the left ductus deferens. Castration, along with surgical resection of the mass, was performed, and histopathology of the mass and ductus deferens was consistent with segmental aplasia of ...
Daisy Johnson, Louisa Price, Marie Beales, Joanna Stephenson   +3 more
wiley   +1 more source

Investigating Crack Resistance Behavior of Polypropylene Using J integral, J‐R Curve and Fractographic Analysis

Fatigue &Fracture of Engineering Materials &Structures, Volume 49, Issue 8, Page 3404-3419, August 2026.
ABSTRACT In this study, the fracture response of polypropylene (PP) was assessed using J‐integral evaluation, J‐R curve construction, and fractography examination. J‐R and load–displacement curves were analyzed to determine critical loads and estimate J‐integral values based on standards established for polymer fracture testing, which led to the ...
N. Choupani, M. Shameli, E. Haddadi, P. Aydiner   +3 more
wiley   +1 more source

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Traction force microscopy of cardiomyocytes

Nature Reviews Cardiology
Maia Lyall
semanticscholar   +3 more sources

The future of traction force microscopy [PDF]

Current Opinion in Biomedical Engineering, 2018
Abstract Animal cells continuously sense and respond to mechanical force. Quantifying these forces remains a major challenge in bioengineering; yet such measurements are essential for the understanding of cellular function. Traction force microscopy is one of the most successful and broadly-used force probing technologies, chosen for the simplicity ...
Huw Colin-York, Marco Fritzsche
exaly   +3 more sources

Simulation and evaluation of 3D traction force microscopy

Computer Methods in Biomechanics and Biomedical Engineering, 2019
Measuring cell-generated forces by Traction Force Microscopy (TFM) has become a standard tool in cell mechanobiology. Although widely used in two dimensional (2D) experiments, only a few methods exist to measure traction in three-dimensional (3D) cell culture, since 3D volumetric high-resolution microscopy and more demanding computational approaches ...
Jess G Snedeker, Nino Wili
exaly   +5 more sources

Compressed sensing traction force microscopy

Acta Biomaterialia, 2015
Adherent cells exert traction forces on their substrate, and these forces play important roles in biological functions such as mechanosensing, cell differentiation and cancer invasion. The method of choice to assess these active forces is traction force microscopy (TFM).
Xavier Trepat, Jonatan Bohr Brask, Marina Uroz   +2 more
exaly   +4 more sources