Results 31 to 40 of about 682,944 (308)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Russia’s foreign trade in raw materials and industrial goods: the impact of integration agreements and sanctions [PDF]

open access: yesBaltic Region
The aim of this study is to evaluate the impact of integration agreements and sanctions on Russia’s foreign trade in raw materials and industrial goods.
Izotov D. A.
doaj   +1 more source

Contesting an International Trade Agreement [PDF]

open access: yesSSRN Electronic Journal, 2018
Abstract We develop a new theoretical political economy framework called a ‘parallel contest’ that emphasizes the political fight over trade agreement (TA) ratification within countries. TA ratification is inherently uncertain in each country because anti- and pro-trade interests contest each other to influence their own government's ratification ...
Cole, MT, Lake, J, Zissimos, B
openaire   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

India’s trade with South and Central Asia: an application of institution-based augmented gravity model

open access: yesFuture Business Journal, 2023
The present study investigates the effect of regional and bilateral trade agreements supported by institutional framework on bilateral trade between India and selected South and Central Asian countries.
Suadat Hussain Wani, Effat Yasmin
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EU Trade and Regulation: Economic and Political Dynamics

open access: yesNotas Económicas, 2019
The EU’s new generation of deep and comprehensive free trade agreements not only promote EU trade but also have a bearing on the shape of the European model and in consequence on the sustainability of the integration project. They reach much further than
Annette Bongardt
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Preferential Trade as a Result of Evolution and Institutionalization of International Trade Agreements [PDF]

open access: yesProblemi Ekonomiki
The article is devoted to the systematization of the prerequisites for the emergence and formation of preferential trade in the context of the historical evolution and institutionalization of international trade agreements. The conclusion of preferential
Kalyuzhna Nataliya H.   +1 more
doaj   +1 more source

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