Results 91 to 100 of about 307,705 (302)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Counterfeits, Copying and Class [PDF]

open access: yes, 2011
Consumers who want to express themselves by wearing contemporary clothing styles should not have to choose between expensive brands and counterfeit products.
Bartow, Ann
core   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Gray Market Goods: A Lighter Shade of Black Symposium: The Controversy over the Importation of Gray Market Goods: Is a Resolution Forthcoming [PDF]

open access: yes, 1987
If a street vendor offers a famous brand-name product for a substantially lower price than one would expect, the average consumer\u27s initial reaction might be that the product had been stolen or was hot - a product of the black market.
Hansen, Hugh C.
core   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Rethinking Trademark Dilution in Jordan: Addressing Ambiguities and Aligning with Global Standards

open access: yesLaws
This paper critically analyses the application of the trademark dilution doctrine under Jordanian trademark law, exposing fundamental deficiencies arising from statutory ambiguity and inconsistent judicial interpretation.
Shatha Majid Shannag, Subhajit Basu
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Marching toward 100% whole genome sequencing

open access: yesFrontiers in Genetics, 2016
Yih-Horng eShiao
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Exploring some trademark issues in metaverse from EU law perspective

open access: yesEastern European Journal of Transnational Relations
This article addresses some issues of trademark protection in virtual worlds. The increasing presence of trademarks in the metaverse, as evidenced by the growing number of trademark applications for virtual goods and services, is likely to intensify ...
Karolina Sztobryn
doaj   +1 more source

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