Results 91 to 100 of about 40,327 (306)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
, 2008 - International Trademark Association First Place Team Best Overall Brief and Oral Argument 2007-2008 Saul Lefkowitz Moot Court Competition Midwestern Regional Oral Arguments February 9, 2008 This competition serves to introduce law students to ...
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Exploring some trademark issues in metaverse from EU law perspective
Eastern European Journal of Transnational RelationsThis article addresses some issues of trademark protection in virtual worlds. The increasing presence of trademarks in the metaverse, as evidenced by the growing number of trademark applications for virtual goods and services, is likely to intensify ...
Karolina Sztobryn
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Marching toward 100% whole genome sequencing
Frontiers in Genetics, 2016 Yih-Horng eShiao
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Well-known trade mark protection: confusion in EU and Japan
, 2009 In this thesis concerning the protection of well-known trade marks against confusion in the European Community Trade Mark (CTM) and Japanese trademark systems, the author critically considers the difficulties in comprehensively defining ‘well-known trade
Onishi, Hiroko
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Based on the assumption that possible future reforms of the Madrid System for the filing and renewal of trademark registration at the international level must be user driven, the paper explored in a series of 23 in-depth interviews, the views of ...
Ghafele, Roya
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