Results 111 to 120 of about 53,842 (293)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Sambal dispute is about trademark infringement

LETTERS: The issue of trademark infringement recently received attention when business owner Khairul Amin, who owns the Sambal Nyet trademark, sent a letter of demand to the founder of Sambal Nyet Khairi.
Ismail, Suzi Fadhilah
core  

Trademark manual of examining procedure.

, 2020
A resource covering federal and state trademark law. Coverage includes the Lanham Trademark Act, U.S. Patent and Trademark Office regulations, the PTO's Trademark Manual of Examining Procedure, the Trademark Trial and Appeal Board Manual of Procedure ...
Kahrl, Robert C.,
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Well-known trade mark protection: confusion in EU and Japan

, 2009
In this thesis concerning the protection of well-known trade marks against confusion in the European Community Trade Mark (CTM) and Japanese trademark systems, the author critically considers the difficulties in comprehensively defining ‘well-known trade
Onishi, Hiroko
core   +1 more source

Income-related biases in international trade : what do trademark registration data tell us? [PDF]

Economists have long recognized that richer countries trade more among themselves than with poorer economies due to a closer match of exporter supply structures and importer preferences.
Mariana Spatareanu, Javorcik,Beata, Carsten Fink   +2 more
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Mass fabrication of PDMS microfluidic devices by injection molding and applications in sensitive 3D spheroid and explant culture

Scientific Reports
This study investigates the use of industrial-grade polydimethylsiloxane (PDMS) for mass production of microfluidic chips through Liquid Silicone Rubber Injection Molding (LSR-IM) technologies.
Raphaël Filion, Amélie St-Georges-Robillard, Henri Chaudoir, Sabrina Ritch, Mamadou Ndongo, Xue Ying Chua, Etienne Laurent, Anne-Marie Mes-Masson, Abdellah Ajji, Thomas Gervais   +9 more
doaj   +1 more source

The Idea of Trademark Rights Valuation as Collaterals: A Financing Solution for Creative Economy Actors

Jurnal Ilmiah Kebijakan Hukum
The renewal of intellectual property-based financing schemes represents a groundbreaking solution to help creative economy actors secure loans using their creative assets.
Sri Handayani, Joni Emirzon, Annalisa Yahanan   +2 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source