Results 101 to 110 of about 2,512,595 (306)
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Anti-obesity effects of Wumeishanzhayin: an integrated lipidomics and transcriptomics study
Frontiers in PharmacologyBackgroundThe global prevalence of adult obesity has increased significantly, affecting over 890 million adults worldwide. Wumeishanzhayin (WMSZY), a formulation derived from four medicinal and edible botanical drugs, has shown efficacy in alleviating ...
Xiao Huang +7 more
doaj +1 more source
Who Loves Ya, David Simon? Notes towards placing The Wire’s depiction of African-Americans in the context of American TV crime drama [PDF]
, 2009 This essay surveyed a number of key shows from the past that purported to convey a liberal viewpoint, and which made race a focus. This was in order to suggest ways in which 'The Wire' might be part of a genre tradition – and equally how it might be seen
Gibb, Jane, Sabin, Roger
core
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
, 2019 While Friends have a strong tradition of activism around the social justice issues of each era, we also tend to spiritualize our faith, disconnecting it from the material world. Environmental concerns are arguably one of the most important social justice
Bock, Cherice
core
Reclusion And The Chinese Eremitic Tradition [PDF]
, 1993 Aat Vervoorn\u27s Men of the Cliffs and Caves is a groundbreaking study of attitudes held by the scholar-official class concerning the issue of service vis-à-vis reclusion, retirement, and withdrawal.
Berkowitz, Alan
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source