Results 51 to 60 of about 146,044 (265)
Cell DivisionBackground Circular RNA (circRNA) and extracellular vesicles (EVs) in tumors are crucial for the malignant phenotype of tumor cells. Nevertheless, the mechanisms and clinical effects of EV-delivered hsa_circ_0090081 in gastric cancer (GC) are unclear ...
Yanjie Mou, Kun Lv
doaj +1 more source
Tradition ... Tradition ... [PDF]
Journal of the Pediatric Infectious Diseases Society, 2014 Ilan, Youngster, Ben Z, Katz
openaire +2 more sources
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Różewicz and Bonhoeffer. On the Margin of the Poem Learning to Walk by Tadeusz Różewicz
Acta Universitatis Lodziensis. Folia Litteraria Polonica, 2016 The departure point of the analysis presented in this article is a poem written by Tadeusz Różewicz learning to walk (nauka chodzenia). The protagonist of the poem is Dietrich Bonhoeffer, who created the theory of “religionless Christianity”.
Przemysław Dakowicz
doaj +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Integrative Cancer TherapiesAim: The aim of this study was to analyse the effiacy of HeXue Tongbi Formula in the treatment of oxaliplatin-induced perpheral neuropathy. Method: An open randomized, non-blind, controlled study was conducted at the First Affiliated Hospital of ...
Lingling Sun MD +5 more
doaj +1 more source
Between the University and the Monastery: The Ethiopian Church and the Transformation of Knowledge
Kulturní StudiaThis article examines the transformations of the Ethiopian Orthodox educational system ʾAbənnat Təmhərt in the context of modernity and digital culture. It argues that the Ethiopian Orthodox Church constitutes a unique case in which education, faith, and
Asrat Tsegaw, Tilahun Tsegaye
doaj +1 more source
Histoire et évolution des appellations d'origine françaises
BIO Web of Conferences, 2019 During the 20th century, wine appellations of origin have largely developed to represent a significant part of the wine production of some countries, especially in Europe. The globalization of the production, trade and consumption of wine is a major fact
Gautier J., Humbert F., Wolikow S.
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source