Results 71 to 80 of about 2,485,749 (291)

Memory, tradition, and Christianization of the Peloponnese [PDF]

, 2015
This work examines the use of memory and tradition in the Christianization of the Peloponnese based on the evidence of the location and topography of churches.
Sweetman, Rebecca Jane
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Between the University and the Monastery: The Ethiopian Church and the Transformation of Knowledge

Kulturní Studia
This article examines the transformations of the Ethiopian Orthodox educational system ʾAbənnat Təmhərt in the context of modernity and digital culture. It argues that the Ethiopian Orthodox Church constitutes a unique case in which education, faith, and
Asrat Tsegaw, Tilahun Tsegaye
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Clinical Efficacy of Hexue Tongbi Formula on Oxaliplatin-Induced Peripheral Neuropathy: A Randomized Controlled Study

Integrative Cancer Therapies
Aim: The aim of this study was to analyse the effiacy of HeXue Tongbi Formula in the treatment of oxaliplatin-induced perpheral neuropathy. Method: An open randomized, non-blind, controlled study was conducted at the First Affiliated Hospital of ...
Lingling Sun MD, Yiying Lv MM, Duo Li MM, Jingyu Feng MD, Zhuangzhong Chen MM, Lizhu Lin MD   +5 more
doaj   +1 more source

What Has History to Do with Philosophy? Insights from the Medieval Contemplative Tradition [PDF]

, 2018
This paper highlights the corrective and complementary role that historically informed philosophy can play in contemporary discussions. What it takes for an experience to count as genuinely mystical has been the source of significant controversy; most ...
Van Dyke, Christina
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Museum Education and Archaeological Ethics: An Approach to the Illicit Trade of Antiquities

Journal of Conservation and Museum Studies, 2014
Many museum educational programs and exhibitions worldwide, designed to communicate to the public the importance of archaeology, adopt a treasure hunt approach often inspired by emblematic mass culture figures, such as Indiana Jones or Lara Croft ...
Vasilike Argyropoulos, Eleni Aloupi-Siotis, Kyriaki Polikreti, Rea Apostolides, Wafaa El Saddik, Raymund Gottschalk, Mona Abd el Nazeer, Marina Vryonidou-Yiangou, Peter Ashdjian, Maria-Christina Yannoulatou, Stefan Simon, Wolfgang Davis, Vasiliki Kassianidou   +12 more
doaj   +1 more source

Impartiality, Close Friendships and the Confucian Tradition [PDF]

, 2017
This article explores the relationship between friendship and morality. Two ideas have been influential in the history of moral philosophy: the impartial standpoint and close friendship.
Lambert, Andrew
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source