Results 81 to 90 of about 3,154,939 (307)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

Advanced Science
Enfumafungin‐type antibiotics, represented by enfumafungin and fuscoatroside, constitute a distinct class of fungi‐derived fernane‐type triterpenoids renowned for their potent antifungal activity.
Yaohui Gao, Jianming Lv, Yue Zhong, Zhiqin Cao, Rui Luo, Yue Qi, Gaoqian Wang, Shaoyang Li, Guodong Chen, Dan Hu, Hao Gao, Xinsheng Yao   +11 more
doaj   +1 more source

Recent progress in the application of hydrophilic interaction liquid chromatography for the separation and analysis of traditional Chinese medicine

Frontiers in Chemistry
Traditional Chinese medicine (TCM), with a history spanning over 2,000 years, contains numerous strongly polar components that are increasingly the focus of pharmaceutical and analytical research.
Yuanyuan Wu, Hui Huang, Xianglong Zhao, Xianglong Zhao, Junhao Lin, Jialiang Guo, Zhengjin Jiang, Kesara Ar-Sanork, Kesara Ar-Sanork, Tao Deng, Dongsheng Xu   +10 more
doaj   +1 more source

DO COLLEGE STUDENTS LEARN BY CORRECTING MISSED EXAM QUESTIONS? [PDF]

This study determines the learning benefit of correcting missed exam questions. The results show that in addition to exams being an assessment tool, they can also be used as a tool for student learning.
Bess, Erin, Green, V. Steven, Schroeter, Christiane   +2 more
core   +1 more source

Assessment in senior outdoor education: A catalyst for change? [PDF]

, 2011
In recent times issues of sustainability and place, and human connectedness and care for outdoor environments, have been the subject of increasing professional dialogue in outdoor education in Aotearoa New Zealand. Attention has been drawn to the ways in
Cosgriff, Marg, Gillespie, Lorna B.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Delivery of miR-29a/29c-3p by serum exosomes promotes osteogenesis through TET3-dependent Sox9 demethylation and PI3K/Akt activation

Journal of Nanobiotechnology
Osteoporosis (OP) is characterized by impaired bone formation, largely attributed to dysfunctional osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs).
Qing Lin, Weipeng Sun, Biyi Zhao, Jiajia Huang, Honghao Huang, Xueshan Jin, Yun Zou, Li Yang, Xiaofeng Zhu, Ronghua Zhang, Xiaoyun Li   +10 more
doaj   +1 more source

AMBRA1 drives gastric cancer progression through regulation of tumor plasticity

Frontiers in Immunology
BackgroundStomach adenocarcinoma (STAD) is an aggressive malignancy characterized by high tumor plasticity and heterogeneity. This study investigates the role of Autophagy and Beclin 1 Regulator 1 (AMBRA1) in regulating tumor plasticity in STAD ...
Liuqi Ye, Danlei Lin, Wen Zhang, Shiji Chen, Yumiao Zhen, Sara Akkouche, Xiaoxu Liang, Cheong-Meng Chong, Hai-Jing Zhong, Hai-Jing Zhong   +9 more
doaj   +1 more source

Assessment of the performance of traditional agroforestry systems in Southwestern Cameroon [PDF]

, 2008
Amid the diversity of farming systems developed in humid tropical zones, a large number is characterized by the combination of perennial and annual plants.
Bikoï, Achille, Chambon, Bénédicte, De Barros, Inacio, Ebongue, Ruth, Ehabe, Ejolle Eugène, Enjalric, Frank, Nguinlong, John Carlos, Rodrigues, Geraldo Stachetti   +7 more
core  

Portable Perimetry Using Eye-Tracking on a Tablet Computer—A Feasibility Assessment [PDF]

, 2019
Purpose: Visual field (VF) examination by standard automated perimetry (SAP) is an important method of clinical assessment. However, the complexity of the test, and its use of bulky, expensive equipment makes it impractical for case-finding.
Bi, W., Crabb, D. P., Jones, P. R., Smith, N. D.   +3 more
core   +1 more source