Results 61 to 70 of about 7,969,703 (297)

Hepatorenal protective effects of essential oils against chemical overexposure induced oxidative damage

open access: yesFrontiers in Pharmacology
Chemical overexposure is a significant concern in both environmental and occupational settings, often leading to oxidative stress and subsequent cellular damage.
Faming Jiang   +6 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Arctic Monitoring and Assessment Programme Assessment 2013: Arctic Ocean Acidification

open access: yes, 2013
Report documenting the findings and recommendations of the first comprehensive assessment of Arctic Ocean acidification (AOA) conducted by the Arctic Monitoring and Assessment Programme (AMAP).
Arctic Monitoring and Assessment Programme
core  

Applications and challenges of traditional Chinese medicine in gastrointestinal disease treatment: A review

open access: yesJournal of Traditional Chinese Medical Sciences
Gastrointestinal (GI) diseases are common multifactorial disorders involving chronic inflammation, epithelial barrier disruption, immune dysregulation, gut microbiota imbalance, and abnormalities in motility and gut–brain interactions.
Aijing Li   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Anti-inflammatory lindenane-type sesquiterpenoid homo-/heterodimers from Chloranthus holostegius: Isolation, structural elucidation, and regulation of NF-κB/JAK pathways

open access: yesIndustrial Crops and Products
Chloranthus holostegius, a perennial herbaceous plant of the family Chloranthaceae, is predominantly distributed in southern China and exhibits significant value in both horticultural and medicinal applications. In this study, nine previously undescribed
Zhao-Chun Zhan   +13 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Widespread increase of functional connectivity in Parkinson’s disease with tremor: A resting-state fMRI study

open access: yesFrontiers in Aging Neuroscience, 2015
Parkinson’s disease (PD) is a clinically heterogeneous disease in the symptomatology dominated by tremor, akinesia or rigidity. Focusing on PD patients with tremor, this study investigated their discoordination patterns of spontaneous brain activity by ...
Delong eZhang   +6 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

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