Results 81 to 90 of about 7,969,703 (297)

Recent progress in the application of hydrophilic interaction liquid chromatography for the separation and analysis of traditional Chinese medicine

Frontiers in Chemistry
Traditional Chinese medicine (TCM), with a history spanning over 2,000 years, contains numerous strongly polar components that are increasingly the focus of pharmaceutical and analytical research.
Yuanyuan Wu, Hui Huang, Xianglong Zhao, Xianglong Zhao, Junhao Lin, Jialiang Guo, Zhengjin Jiang, Kesara Ar-Sanork, Kesara Ar-Sanork, Tao Deng, Dongsheng Xu   +10 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Todays’ Assessment: Between Traditional and Alternative Assessment

Jurnal Syntax Transformation
Assessment plays a pivotal role in EFL (English as a Foreign Language) instruction, yet Indonesian teachers continue to struggle with designing valid, reliable, and pedagogically appropriate instruments—defaulting to traditional formats that inadequately capture learners' productive language skills.
openaire   +1 more source

Delivery of miR-29a/29c-3p by serum exosomes promotes osteogenesis through TET3-dependent Sox9 demethylation and PI3K/Akt activation

Journal of Nanobiotechnology
Osteoporosis (OP) is characterized by impaired bone formation, largely attributed to dysfunctional osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs).
Qing Lin, Weipeng Sun, Biyi Zhao, Jiajia Huang, Honghao Huang, Xueshan Jin, Yun Zou, Li Yang, Xiaofeng Zhu, Ronghua Zhang, Xiaoyun Li   +10 more
doaj   +1 more source

AMBRA1 drives gastric cancer progression through regulation of tumor plasticity

Frontiers in Immunology
BackgroundStomach adenocarcinoma (STAD) is an aggressive malignancy characterized by high tumor plasticity and heterogeneity. This study investigates the role of Autophagy and Beclin 1 Regulator 1 (AMBRA1) in regulating tumor plasticity in STAD ...
Liuqi Ye, Danlei Lin, Wen Zhang, Shiji Chen, Yumiao Zhen, Sara Akkouche, Xiaoxu Liang, Cheong-Meng Chong, Hai-Jing Zhong, Hai-Jing Zhong   +9 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Traditional Arts Indiana Presents The 2019 Indiana Heritage Fellowships [PDF]

, 2019
A program booklet from the first Indiana Heritage Fellowship Awards Ceremony: April 27, 2019 at the Mathers Museum of World Cultures Indiana University, Bloomington.Indiana Heritage Fellowship awards recognize traditional artists who make outstanding ...
Traditional Arts Indiana
core  

SMYD5-BRD4 Interaction Drives Hepatocellular Carcinoma Progression: A Combined in Silico and Experimental Analysis

Pharmaceuticals
Background/Objectives: Hepatocellular carcinoma (LIHC) poses significant challenges due to limited targeted therapeutic options. This study investigates SMYD5, an oncogene implicated in the pathogenesis of LIHC, and its interaction with the BRD4 protein.
Mingye Hu, Shiji Chen, Yumiao Zhen, Xin Wang, Yiwen Zhong, Xiaoxu Liang, Cheong-Meng Chong, Hai-Jing Zhong   +7 more
doaj   +1 more source

Capturing the Real-Time Hydrolytic Degradation of a Library of Biomedical Polymers by Combining Traditional Assessment and Electrochemical Sensors. [PDF]

Biomacromolecules, 2021
Fuoco T, Cuartero M, Parrilla M, García-Guzmán JJ, Crespo GA, Finne-Wistrand A.   +5 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source