Results 81 to 90 of about 890,547 (267)

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Targeting FAPα-positive lymph node metastatic tumor cells suppresses colorectal cancer metastasis

Acta Pharmaceutica Sinica B
Lymphatic metastasis is the main metastatic route for colorectal cancer, which increases the risk of cancer recurrence and distant metastasis. The properties of the lymph node metastatic colorectal cancer (LNM-CRC) cells are poorly understood, and ...
Shuran Fan, Ming Qi, Qi Qi, Qun Miao, Lijuan Deng, Jinghua Pan, Shenghui Qiu, Jiashuai He, Maohua Huang, Xiaobo Li, Jie Huang, Jiapeng Lin, Wenyu Lyu, Weiqing Deng, Yingyin He, Xuesong Liu, Lvfen Gao, Dongmei Zhang, Wencai Ye, Minfeng Chen   +19 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Targeted Isolation of ω-3 Polyunsaturated Fatty Acids from the Marine Dinoflagellate Prorocentrum lima Using DeepSAT and LC-MS/MS and Their High Activity in Promoting Microglial Functions

Marine Drugs
In this study, we integrated HSQC-based DeepSAT with UPLC-MS/MS to guide the isolation of omega-3 polyunsaturated fatty acid derivatives (PUFAs) from marine resources.
Chang-Rong Lai, Meng-Xing Jiang, Dan-Mei Tian, Wei Lu, Bin Wu, Jin-Shan Tang, Yi Zou, Song-Hui Lv, Xin-Sheng Yao   +8 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Morphology Effect of Puffball Spores on Hemostasis: A Promising Solution for Hemostatic Challenges

Advanced Science
Hemostatic materials play a crucial role in wound healing by promoting blood concentration or releasing procoagulant factors. While hydrophilic hemostatic materials are effective, they may cause excessive blood loss and difficulty removing from the wound.
Xuechang Pei, Yue Feng, Yanru Wu, Jie Zhang, Jianlan Li, Shutai Jiang, Huijun Huang, Ping Qin, Guoqing Li, Xinrui Guo, Mingxian Liu, Chuanxi Wang, Hao Gao   +12 more
doaj   +1 more source

Hepatoprotective efficacy of low molecular weight chicken intestine peptide against acute alcohol-induced liver injury

Food Science and Human Wellness
Food-derived bioactive peptides exhibit good health-promoting effects. In this study, low molecular weight chicken intestine peptide (CIP) below 2 kDa is prepared through trypsin hydrolysis of chicken intestine and ultrafiltration, and the ...
Changyu Yan, Xinxing Chen, Rong Wang, Qianqian Zhu, Guilan Xiong, Chengxi Guan, Yanping Wu, Wanyang Sun, Lei Liang, Haibiao Gong, Jun Zheng, Kezhu Wang, Weixin Zheng, Longfei Xia, Yi-Fang Li, Shu-Hua Ouyang, Hiroshi Kurihara, Rong-Rong He   +17 more
doaj   +1 more source

How to assess? Perceptions and preferences of undergraduate medical students concerning traditional assessment methods. [PDF]

BMC Med Educ, 2020
Holzinger A, Lettner S, Steiner-Hofbauer V, Capan Melser M.   +3 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1

Cell Death and Disease
Understanding the mechanisms underlying chemoresistance is critical for improving cancer therapies. SIN1 plays a pivotal role in maintaining mTORC2 integrity and activation, which regulates key cellular processes.
Yalei Wen, Caishi Zhang, Mingchao Liang, Xiao Yang, Hu Zeng, Rui Wan, Xiuqing Ma, Lei Huang, Mei Li, Qiushi Zhang, Liheng Li, Shengying Qin, Tongzheng Liu   +12 more
doaj   +1 more source