Results 91 to 100 of about 54,879 (249)

Sentinel factors for mild cognitive impairment in type 2 diabetes mellitus and their interaction mechanisms: a narrative review with network analysis perspective

open access: yesFrontiers in Endocrinology
Type 2 diabetes mellitus (T2DM) is a global chronic metabolic epidemic, and affected patients face a 1.5-fold higher risk of mild cognitive impairment (MCI) — a reversible pre-dementia stage — than non-diabetic populations.
Qiongqiong Sun   +3 more
doaj   +1 more source

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li   +6 more
wiley   +1 more source

The Application of Traditional Chinese Medicine-Derived Formulations in Cancer Immunotherapy: A Review

open access: yesCancer Management and Research
Yanyun Li,1 Changying Li,2 Junzi Fan,3 Yutong Liu,1 Yincong Xu,4 Guowei Pang1 1School of Acupuncture and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People’s Republic of China; 2School of Ophthalmology and optometry ...
Li Y, Li C, Fan J, Liu Y, Xu Y, Pang G
doaj  

Mechanism of traditional Chinese medicine in elderly diabetes mellitus and a systematic review of its clinical application

open access: yesFrontiers in Pharmacology
Objective: Affected by aging, the elderly diabetes patients have many pathological characteristics different from the young people, including more complications, vascular aging, cognitive impairment, osteoporosis, and sarcopenia.
Qiqi Zhang   +7 more
doaj   +1 more source

Systematic Review and Meta‐Analysis: Plant‐Based Therapy for Irritable Bowel Syndrome

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Irritable bowel syndrome (IBS) is a common disorder of brain‐gut interaction that presents with abdominal pain, bloating associated with variable stool consistency. Many IBS patients prefer plant‐based preparations to pharmacological therapy; however, the utility of this approach is not well established.
Anselm Meyer   +8 more
wiley   +1 more source

The association between red blood cell distribution width‐to‐albumin ratio and risk of insomnia: A cross‐sectional analysis of National Health and Nutrition Examination Survey and Chinese clinical data

open access: yesSleep Research, EarlyView.
Abstract Background The red blood cell distribution width‐to‐albumin ratio (RAR) is a novel composite biomarker of inflammation and nutritional status, yet its association with insomnia and underlying mechanisms remain poorly understood. Objective To investigate the association between the RAR and insomnia in two independent cohorts, comprising a ...
Jingying Ma   +7 more
wiley   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

open access: yesVIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang   +7 more
wiley   +1 more source

Mechanisms of He Shi Yu Lin formula in treating premature ovarian insufficiency: insights from network pharmacology and animal experiments

open access: yesJournal of Ovarian Research
Objective He Shi Yu Lin Formula (HSYLF) is a clinically proven prescription for treating premature ovarian insufficiency (POI), and has shown a good curative effect. However, its molecular mechanisms are unclear.
Yun Huang, Qin Zhang, Dan Shen, Xi Bao
doaj   +1 more source

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