Results 101 to 110 of about 7,584,615 (297)

Artificial Intelligence‐Driven Network Pharmacology: A Methodological Paradigm Shift Bridging Traditional Wisdom and Modern Science

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence is redefining network pharmacology (NP). By integrating knowledge graph engineering, geometric deep learning, multiomics anchoring, and generative reasoning, AI‐driven NP (AI‐NP) transforms static target mapping into dynamic, predictive modeling.
Cong Wang, Sile Hu, Rigahai Ji, Riguna A, Siqige Hao, Ma Zhuo, Yi‐Hung Chen, Bisihalatu Hu, Ulana Bai, Xigui Hada   +9 more
wiley   +1 more source

Baihe Zhimu Decoction ameliorates anxious depression via PI3K/AKT/mTOR pathway‐mediated neuroprotection and inhibition of hippocampal neuronal apoptosis

Animal Models and Experimental Medicine, EarlyView.
Baihe Zhimu Decoction alleviates anxious depression‐like behaviors and protects hippocampal neurons. Chemical profiling and network pharmacology reveal multiple active components acting via the PI3K/AKT/mTOR pathway, enhancing neuronal survival and function, as confirmed by multi‐level in vitro and in vivo validation.
Yuanshan Han, Kexin He, Haolan Yang, Jiacheng Dai, Ronglin Chen, Yang Liu, Yuhong Wang, Lin Tang, Hongqing Zhao   +8 more
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Clinical Practice Guideline for the Integrated Traditional Chinese and Western Medicine Diagnosis and Treatment of Cancer-related Fatigue [PDF]

Cancer-related fatigue (CRF) is a painful, persistent, subjective, physical, emotional or cognitive feeling of fatigue caused by multiple factors related to cancer or cancer treatment, which does not match the amount of recent activity and seriously ...
CUI Yiyuan, YAN Yijing, WANG Ying, MENG Xiangju, ZHANG Qinglin, LIU Lixing, LI Sicong, FENG Li, The Working Group for the Clinical Practice Guideline for the Cancer-related Fatigue with Integrated Traditional Chinese and Western Medicine
core   +1 more source

Establishing an EU-China consortium on traditional Chinese medicine research. [PDF]

, 2010
Traditional Chinese medicine (TCM) is widely used in the European Union (EU) and attracts intense research interests from European scientists. As an emerging area in Europe, TCM research requires collaboration and coordination of actions.
Tai-Ping Fan, ElNezami, HS, Guo, De-an, Qihe Xu, Uzuner Halil, Dias, Alberto Carlos Pires, Hani S El-Nezami, Fan Tai-Ping, Uzuner, H, El-Nezami Hani S, Xu, Qihe, Dias Alberto, Guo, DA, Alberto Dias, Uzuner, Halil, Guo De-an, El-Nezami, Hani, El-Nezami, Hani S, Fan, Tai-Ping, Xu Qihe, Xu, Q, Dias, A, Dias, Alberto, De-an Guo, Halil Uzuner, Fan, TP   +25 more
core   +3 more sources

The State of Traditional Chinese Medicine (TCM) School in Singapore

Kampo Medicine, 2008
2003年新加坡中医学院を見学し，シンガポールの中医学校制度について報告した。教材はシンガポール独自のものでなく，中華人民共和国製の教材を使用していた。1994年シンガポール保健省は，伝統中医薬委員会に中医学（TCM）の診療についてのレビューを行うよう指示を出し，患者の利益と安全を守ることを調べるように勧告した。1995年シンガポールのTCMの診療をコントロールし，トレーニングの水準を上げるようにと勧告した委員会の報告が出された。カリキュラム改変の指示を受け，1996年政府保健省の指示に沿う形で，中医学院は西洋医学の基礎学習を充実させ，3年全日制と6年夜間部2コースの設置となった。2000年より全国統一試験が始まり，資格として認められるようになった。シンガポールは ...
MATSUOKA, Takanori, MURASAKI, Toru, KURIBAYASHI, Hideki   +2 more
openaire   +2 more sources

Integrated spherical nucleic acid nanoreactor mobilizes targeted PD‐L1 proteolysis and cuproptosis for robust breast cancer immunotherapy

BMEMat, EarlyView.
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li, Honglin Huang, Qianyi Zeng, Li Zeng, Ziman Yang, Jinyang Shen, Shun Li, Hong Yang, Yiyao Liu, Chunhui Wu   +9 more
wiley   +1 more source

Contemplation on Development of Traditional Chinese Medicine Rehabilitation Science

康复学报, 2017
Although the concept of Traditional Chinese Medicine Rehabilitation Science began in the 1980s, a lot of rehabilitation treatments were recorded on ancient classics of traditional Chinese medicine (TCM). For example, Huangdi Neijing emphasizes regulating
Xiaodong FENG
doaj  

Interface fluid syndrome caused by the corneal perforation injury after small incision lenticule extraction: a case report

BMC Ophthalmology
Background To report a case of interface fluid syndrome (IFS) following traumatic corneal perforation repair after small incision lenticule extraction (SMILE).
Xu Jing, Li Congxin, Zhang Xiaoyan, Yuan Yue, Li Jiao, Zu Peipei, Wang Yirong, Wen Ying, Bi Hongsheng   +8 more
doaj   +1 more source

Developing Chinese herbal-based functional biomaterials for tissue engineering

Heliyon
The role of traditional Chinese medicine (TCM) in treating diseases is receiving increasing attention. Chinese herbal medicine is an important part of TCM with various applications and the active ingredients extracted from Chinese herbal medicines have ...
Wenhui Ge, Yijun Gao, Liming He, Zhisheng Jiang, Yiyu Zeng, Yi Yu, Xiaoyan Xie, Fang Zhou   +7 more
doaj   +1 more source