Results 81 to 90 of about 7,584,615 (297)

Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on "system to system" mode [PDF]

, 2012
Background Shuanglong formula (SLF), a Chinese medicine composed of panax ginseng and salvia miltiorrhiza exhibited significant effect in the treatment of myocardial infarction (MI) in clinical. Because of the complex nature and lack of stringent quality
Yuan-Yuan Xie, Chen, Xi, Lv Shu-Feng, Liang, Q-L, Xu, Qing-Bo, Qing-Bo Xu, Liang Qiong-Lin, Cheng, Yi-Jun, Zhang, Q-L, Rong Gao, Xu, Q-B, Yi-Ming Wang, Zhang, Rong-Li, Xue Li, Gao, Rong, Lv, Shu-Feng, Zhang Rong-Li, Shu-Feng Lv, Xu Qing-Bo, Xi Chen, Xue-Mei Fan, Liang, Xiao-Ping, Liang Xiao-Ping, Jun Wu, Wu Jun, Xie Yuan-Yuan, Luo Guo-An, Zhang, Qing-Li, Zhang Hong-Yang, Xiao-Ping Liang, Gao, R, Luo, Guo-An, Xie, Yuan-Yuan, Zhang, Hong-Yang, Cheng, Y-J, Fan Xue-Mei, Zhang Qing-Li, Liang, Qiong-Lin, Xiao, Q-Z, Zhang, H-Y, Xiao, Qing-Zhong, Zhang, R-L, Yi-Jun Cheng, Chen, X, Wu, Jun, Xie, Y-Y, Luo, G-A, Qing-Li Zhang, Qiong-Lin Liang, Wang, Yi-Ming, Qing-Zhong Xiao, Lv, S-F, Gao Rong, Li Xue, Wang, Y-M, Wu, J, Fan, Xue-Mei, Cheng Yi-Jun, Hong-Yang Zhang, Wang Yi-Ming, Fan, X-M, Li, Xue, Liang, X-P, Guo-An Luo, Chen Xi, Xiao Qing-Zhong, Li, X, Rong-Li Zhang   +67 more
core   +1 more source

Targeting Macrophage‐Mediated Lymphatic Immunosuppression to Prevent Tumor Recurrence After Microwave Ablation

Advanced Science, EarlyView.
Incomplete microwave ablation induces animmunosuppressive microenvironment in tumor‐draining lymph nodes. An albumin‐based lipoprotein nanosystem enables coordinated delivery of immunomodulators to tumor‐draining lymph nodes and residual tumors, reverses post‐ablation immunosuppression, suppresses residual tumor growth, and promotes durable antitumor ...
Xuexia Shan, Yuting Shen, Xiaodong Hou, Fengshan Jin, Shaoyue Li, Weichen Xu, Weiwei Ren, Xiaowan Bo, Qiuyan Li, Shuo Liu, Weifan Hao, Chengzhong Peng, Huixiong Xu, Liping Sun, Wenwen Yue   +14 more
wiley   +1 more source

Forest plot of the TCM relative clinical score for myasthenia gravis; outcome: TCM relative clinical score; TCM, Traditional Chinese Medicine.

Forest plot of the TCM relative clinical score for myasthenia gravis; outcome: TCM relative clinical score; TCM, Traditional Chinese Medicine.
Dongxun Xu (16620417), Hongxian He (16620414), Li Zeng (77324), Kaixin Ren (4794777), Hua Xue (469826)   +4 more
core   +1 more source

Epithelial SLC25A20 Deficiency Drives Immunosuppressive Neutrophil Remodeling via ARG1 Palmitoylation to Promote Colorectal Cancer

Advanced Science, EarlyView.
SLC25A20 deficiency in tumor cells compromises mitochondrial LCFA transport, which suppresses FAO and drives compensatory release of palmitic acid‐enriched lipids into the TME. These tumor‐derived palmitic acids are taken up by TANs, promoting ZDHHC18‐catalyzed ARG1 palmitoylation.
Yue Han, Tian‐Yuan Tan, Bin Zhang, Ye‐Bin Fu, Wen Chen, Min‐Hui Yang, Yi‐Qing Wang, Yan‐Qing Ding, Shuang Wang   +8 more
wiley   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

Role of Traditional Chinese Medicine in Modern Healthcare [PDF]

, 2013
Theories of Traditional Chinese Medicine (TCM) Traditional Chinese Medicine (TCM), a form of complementary and alternative medicine (CAM), has been practiced for over 2500 years, and approaches health as an interrelated and holistic state of being. Using
Dun, Gealina
core   +1 more source

Clinical Practice Guidelines in Traditional Chinese Medicine Rehabilitation—Rheumatoid Arthritis

, 2020
Rheumatoid arthritis (RA) is an autoimmune disease characterized by erosive arthritis, eventually leading to joint deformity and loss of function. To standardize the operating standards of RA for traditional Chinese medicine (TCM) and better guide ...
Chao ZHANG, Yuming NIU, Bao ZHANG, Guohong WEN, Junhua WANG, Working Group on Setting up Standardization Guidelines of Rheumatoid Arthritis in Traditional Chinese Medicine Rehabilitation, Rui WANG, Lei JIANG, Hanyu CHEN, Xinggang FANG, Jie LUO, Peimin LAN, Zengfeng CHEN, Jiandong WEI, Su ZHENG, Rui LI, Feng GAO, Dongyue LENG, Yong CHEN   +18 more
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FAK Mediated Coordination of Extracellular Matrix Remodeling and Cellular Mechanics Impairs Nanomedicine Delivery in Solid Tumors

Advanced Science, EarlyView.
FAK orchestrates a mechanical barrier limiting nanomedicine accumulation in solid tumors by coupling ECM remodeling with cytoskeletal tension. Genetic or pharmacological FAK inhibition dismantles this barrier, enhances clathrin‐mediated uptake and penetration, and overcomes delivery limitations to improve antitumor efficacy.
Tian Zhao, Hao Wu, Yujie Qin, Jingfei Zhu, Ye Huang, Wei Chen, Jiaxuan Yu, Xiang Qin, Shun Li, Junjie Li, Tingting Li, Yiyao Liu   +11 more
wiley   +1 more source

Traditional Chinese Medicine in Australia

, 1997
In 1996 a government review of Traditional Chinese Medicine (TCM) was commissioned by the Victorian, Mew South Wales and Queensland health departments with a view to making recommendations on the need for occupational regulation of TCM practitioners ...
Chang, S, Kermode, Stephen, Bensoussan, Alan, Myers, Stephen P   +3 more
core   +1 more source

Tubocapsenolide A Overcomes Oxaliplatin Resistance in Colorectal Cancer by Targeting PLK1 to Impair CEP55–ESCRT‐Associated Vesicular Damage Clearance

Advanced Science, EarlyView.
Oxaliplatin‐resistant colorectal cancer cells utilize a previously unappreciated PLK1‐CEP55‐ESCRT‐driven vesicular extrusion mechanism to clear L‐OHP‐induced cellular damage. The natural withanolide Tubocapsenolide A directly targets and inhibits PLK1 to disrupt this specific damage‐clearance machinery. This blockade induces severe nucleolar stress and
Yueying Yang, Jing Liang, Lu Wang, Hongyan Zhang, Zhiruo Zhang, Yang Liu, Rui Zhu, Wen Xu, Shaohua Xu, Dejuan Sun, Ke Xiang, Yali Wang, Zhimin Fan, Zheng Wang, Hua Li, Lixia Chen   +15 more
wiley   +1 more source