Results 131 to 140 of about 75,375 (316)

Ethanolic Extract of Traditional Chinese Medicine (TCM) Gamboge Inhibits Colon Cancer via the Wnt/Beta-Catenin Signaling Pathway in an Orthotopic Mouse Model [PDF]

open access: bronze, 2018
Wei Wang   +10 more
openalex   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

open access: yesIntegrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu   +3 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

open access: yesBritish Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu   +6 more
wiley   +1 more source

Sentinel factors for mild cognitive impairment in type 2 diabetes mellitus and their interaction mechanisms: a narrative review with network analysis perspective

open access: yesFrontiers in Endocrinology
Type 2 diabetes mellitus (T2DM) is a global chronic metabolic epidemic, and affected patients face a 1.5-fold higher risk of mild cognitive impairment (MCI) — a reversible pre-dementia stage — than non-diabetic populations.
Qiongqiong Sun   +3 more
doaj   +1 more source

Advancements in Inorganic Chiral Nanomaterials for Anti‐Tumor Immunotherapy

open access: yesCancer Science, EarlyView.
Schematic illustration of how inorganic chiral nanomaterials enhance immune activation to promote tumor cell elimination through targeted delivery, immunogenic cell death, and immune microenvironment modulation. ABSTRACT While the past decade has witnessed unprecedented technological advancements, cancer remains a major health threat, with conventional
Siyu Chen   +9 more
wiley   +1 more source

The Application of Traditional Chinese Medicine-Derived Formulations in Cancer Immunotherapy: A Review

open access: yesCancer Management and Research
Yanyun Li,1 Changying Li,2 Junzi Fan,3 Yutong Liu,1 Yincong Xu,4 Guowei Pang1 1School of Acupuncture and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People’s Republic of China; 2School of Ophthalmology and optometry ...
Li Y, Li C, Fan J, Liu Y, Xu Y, Pang G
doaj  

The gene expression profiles in response to 102 traditional Chinese medicine (TCM) components: a general template for research on TCMs [PDF]

open access: gold, 2017
Chao Lv   +10 more
openalex   +1 more source

Irradiated Liver Cancer Cell Vaccine Transfected With GM‐CSF Induces Specific and Long‐Lasting Anti‐tumour Immunity Through the Synergistic Effect of Oxidised mtDNA and GM‐CSF

open access: yesCell Proliferation, EarlyView.
Song et al. developed an mGM‐CSF‐loaded, liver cancer cell‐based vaccine that potently activated dendritic cells and elicited tumour‐specific T cell responses. Mechanistically, radiation‐induced oxidative damage to mitochondrial DNA in cancer cells triggers the cGAS‐STING pathway in DCs, which synergizes with mGM‐CSF‐driven JAK2‐STAT3 signalling to ...
Zhiruo Song   +15 more
wiley   +1 more source

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