Pien Tze Huang (PZH) as a Multifunction Medicinal Agent in Traditional Chinese Medicine (TCM): a review on cellular, molecular and physiological mechanisms. [PDF]
Cancer Cell Int, 2021 Chen Z.
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Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
Advanced Science, Volume 13, Issue 44, 7 August 2026.MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
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Beware of the Relationship between Sleep Quality and Cognitive Impairment [Letter]
Nature and Science of SleepXiaoying Liu, Hui Chen, Changde Wang Neurology Department, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200011, People’s Republic of ChinaCorrespondence: Changde Wang, Neurology Department ...
Liu X, Chen H, Wang C
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Cancer Medicine, Volume 15, Issue 8, August 2026.ABSTRACT Background Gastric cancer is a major global health concern characterized by high incidence and mortality rates. One of the key challenges in treating gastric cancer is the development of resistance to chemotherapy drugs like cisplatin (DDP). This study aimed to investigate the efficacy of Zuo Jin Wan (ZJW), a traditional Chinese medicine, in ...
Zhuo Zhao +6 more
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How does the dual policy-the C-DRG-based reimbursement system and subsidy policy for appropriate Traditional Chinese Medicine (TCM) techniques-influence physicians' choice of disease treatment methods in TCM hospitals? [PDF]
Health Econ RevZhang J, Liu J, Qu L, Duan Z.
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Clonal Hematopoiesis in Colorectal Cancer: Mechanisms and Implications
Cancer Medicine, Volume 15, Issue 8, August 2026.ABSTRACT Clonal hematopoiesis (CH) arises from the expansion of hematopoietic stem and progenitor cells bearing somatic mutations, often in genes linked to epigenetic regulation and inflammation. Once considered a benign age‐related phenomenon, CH has gained increasing attention for its potential to influence cancer biology beyond hematologic ...
Chenyue Xia, Yi Lu, Jinhui Gu
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Clinical Case Reports, Volume 14, Issue 8, August 2026.This flowchart systematically outlines the full diagnostic and therapeutic pathway of mammary Paget's disease with ipsilateral multifocal breast cancer, covering preoperative radiological assessment, postoperative histopathological confirmation of inter‐lesional molecular heterogeneity, individualized multimodal treatment, recurrence‐free follow‐up ...
Hongyu Cheng, Jiayin Tang, Chang Yao
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Evaluating the Traditional Chinese Medicine (TCM) Officially Recommended in China for COVID-19 Using Ontology-Based Side-Effect Prediction Framework (OSPF) and Deep Learning. [PDF]
J Ethnopharmacol, 2021 Wang Z +5 more
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Computational screening and molecular docking of compounds from Traditional Chinese Medicine (TCM) by targeting DNA topoisomerase I to design potential anticancer drugs. [PDF]
PLoS OneShimu MSS.
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Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.SLC7A5‒Kyn/XANA signalling activates AhR to drive EMT and metastatsis. SLC7A5 knockdown enhances macrophage antigen presentation and reverses CD8+ T‐cell exhaustion. SLC7A5 knockdown induces antigen‐driven and IgG‐secreting B‐cell clonal expansion. Combination of SLC7A5 inhibition and anti‐PD‐1 therapy offers clinical targeting.
Yaohao Luo +8 more
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