Results 151 to 160 of about 54,235 (259)

Review of the Efficacy and Mechanisms of Traditional Chinese Medicine for Treating Multi-Organ Damage in Wilson’s Disease

Drug Design, Development and Therapy
Hong Chen,1,* Xie Wang,1,* Le Tang,2 Yue Pu,1 Ying Ma,1 Hao Ye,1 Juan Zhang1 1Department of Neurology, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, 230031, People’s Republic of China; 2Department of ...
Chen H, Wang X, Tang L, Pu Y, Ma Y, Ye H, Zhang J   +6 more
doaj  

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, Volume 13, Issue 35, 24 June 2026.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

How does the dual policy-the C-DRG-based reimbursement system and subsidy policy for appropriate Traditional Chinese Medicine (TCM) techniques-influence physicians' choice of disease treatment methods in TCM hospitals? [PDF]

Health Econ Rev
Zhang J, Liu J, Qu L, Duan Z.
europepmc   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, Volume 13, Issue 35, 24 June 2026.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

The mediating effect of traditional Chinese medicine (TCM) health literacy between TCM culture promotion and residents' health status. [PDF]

Front Public Health
Zhang X, Hong X, Zhang Z.
europepmc   +1 more source

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

Advanced Science, Volume 13, Issue 33, 15 June 2026.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang, Wanhui Dong, Jian Chen, Zhangjie Zhou, Shujuan Fu, Tingting Wu, Haiyan Jiang, Zhiying Wang, Zhixian Zhong, Yi Zhong   +9 more
wiley   +1 more source

Depression and Gastrointestinal Health Abnormalities: Treatment Approaches from the Perspective of Traditional Chinese Medicine

Neuropsychiatric Disease and Treatment
Ke Lu,1,2,* Amei Tang,3,* Yang Liu,1 Lingji Li,1 Rongze Fang,1 Shunliang Zhang,2 Yexin Chen,2 Feng Cao2 1School of Basic Chinese Medicine (Qihuang College), Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, People’s ...
Lu K, Tang A, Liu Y, Li L, Fang R, Zhang S, Chen Y, Cao F   +7 more
doaj  

Evaluating the Traditional Chinese Medicine (TCM) Officially Recommended in China for COVID-19 Using Ontology-Based Side-Effect Prediction Framework (OSPF) and Deep Learning. [PDF]

J Ethnopharmacol, 2021
Wang Z, Li L, Song M, Yan J, Shi J, Yao Y.   +5 more
europepmc   +1 more source

Clinical Study on Combining Traditional Chinese Medicine With Acupuncture for Treating Insomnia Accompanied by Anxiety

Brain and Behavior, Volume 16, Issue 6, June 2026.
In treating Qi stagnation type insomnia, the combination of traditional Chinese medicine and acupuncture can improve sleep quality, alleviate anxiety and depression, and improve physical fitness. Compared to using traditional Chinese medicine decoction alone for treatment, the combination of traditional Chinese medicine decoction and acupuncture has ...
Xue‐Wen Mao, Peng Bai
wiley   +1 more source

Computational screening and molecular docking of compounds from Traditional Chinese Medicine (TCM) by targeting DNA topoisomerase I to design potential anticancer drugs. [PDF]

PLoS One
Shimu MSS.
europepmc   +1 more source