Results 141 to 150 of about 7,584,615 (297)

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

open access: yesiNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang   +3 more
wiley   +1 more source

Mechanisms of He Shi Yu Lin formula in treating premature ovarian insufficiency: insights from network pharmacology and animal experiments

open access: yesJournal of Ovarian Research
Objective He Shi Yu Lin Formula (HSYLF) is a clinically proven prescription for treating premature ovarian insufficiency (POI), and has shown a good curative effect. However, its molecular mechanisms are unclear.
Yun Huang, Qin Zhang, Dan Shen, Xi Bao
doaj   +1 more source

Establishment and Application of a Quantitative Lipemia Index as a Novel Indicator for Assessing Lipemic Interference in Clinical Chemistry

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
A rigorously validated quantitative lipemia index (LI) assay was established for direct serum turbidity measurement. This standardized LI metric demonstrated significantly stronger correlation with lipemic interference (rs = 0.822) than conventional triglyceride concentration (rs = 0.770), consistent with its direct measurement of optical turbidity ...
Haifeng Xie   +5 more
wiley   +1 more source

Bridging Evidence Synthesis and Clinical Relevance in Blood-Letting Therapy for Knee Osteoarthritis: Methodological Reflections on a Meta-Analysis [Response to Letter]

open access: yesJournal of Pain Research
Shuai Dong,1 Duan-Yu Mou,2 Dong-Sheng Qiu,3 Guo-Ping Ye,3 Xi Wu11College of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, People’s Republic of China; 2Affiliated Hospital of Chengdu ...
Dong S, Mou DY, Qiu DS, Ye GP, Wu X
doaj  

Application of Metabolomics and Traditional Chinese Medicine for Type 2 Diabetes Mellitus Treatment

open access: yes, 2023
Jing Li,1,* Na Zhu,2,* Yaqiong Wang,2 Yanlei Bao,3 Feng Xu,2 Fengjuan Liu,2 Xuefeng Zhou2 1Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, People’s Republic of China; 2Clinical Trial Research Center, Affiliated Qingdao
Zhu N   +6 more
core  

Shikonin Promotes Apoptosis in Multiple Myeloma Cells Through the PKM2‐AMPK‐PGC1α Metabolic Axis

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
High PKM2 expression in MM is associated with a poor prognosis. Shikonin represents a promising PKM2‐targeted agent for MM therapy, offering a unique metabolic intervention strategy to improve drug resistance, bone disease, and the immune microenvironment. ABSTRACT Background Multiple myeloma (MM) is an incurable plasma malignancy.
Fengping Peng   +7 more
wiley   +1 more source

Knowledge Gaps, Treatment Preferences, and Unmet Clinical Needs Among Patients With Inflammatory Bowel Disease: A Cross‐Sectional Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study utilized a cross‐sectional survey via a structured questionnaire to evaluate disease‐related knowledge, treatment preferences, and unmet needs among 200 adults with confirmed inflammatory bowel disease (IBD) at a tertiary referral center.
Yi‐Chen Wu   +11 more
wiley   +1 more source

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