Results 191 to 200 of about 65,860 (319)

Dihydrotanshinone I Targets PGAM1 to Induce SYVN1‐Mediated Ubiquitination and Suppress Glycolysis in Hepatocellular Carcinoma

open access: yesPhytotherapy Research, EarlyView.
DHT Induced SYVN1‐Mediated PGAM1 Degradation Blocks HCC Glycolysis. ABSTRACT Phosphoglycerate mutase 1 (PGAM1) is a glycolytic enzyme frequently overexpressed in hepatocellular carcinoma (HCC), contributing to tumor progression through aberrant glycolysis.
Ru Xu   +11 more
wiley   +1 more source

An Up‐to‐Date Review of Traditional Chinese Medicine in the Treatment of Atherosclerosis: Components, Mechanisms, and Therapeutic Potentials

open access: yesPhytotherapy Research, EarlyView.
Traditional Chinese medicine in atherosclerosis: multi‐target modulation of pathogenesis. ABSTRACT Atherosclerosis is a chronic inflammatory disease and a major global health concern. In recent years, traditional Chinese medicines (TCMs) have demonstrated multi‐target therapeutic potential against atherosclerosis by modulating inflammatory responses ...
Dilaram Nijat   +5 more
wiley   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

open access: yesSmart Molecules, EarlyView.
Schematic illustration of acute kidney injury and iron metabolism (By Figdraw). Image for iron metabolism, including uptake, storage, utilization, export: Reproduced with permission. Abstract Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates.
Xinyu Tan   +4 more
wiley   +1 more source

Ionogel‐Dominated Wearable Sensors for Reliable Health Monitoring

open access: yesSusMat, EarlyView.
Ionogels have emerged as promising materials for health monitoring due to their flexibility, thermal stability, and ionic conductivity, yet challenges remain in ensuring reliable performance. This review mainly focuses on the structure‐performance relationships of ionogels towards long‐term health monitoring, including precise designs of robust ...
Wenzhe Xiao   +7 more
wiley   +1 more source

Multifunctional tumor vaccines carrying thalidomide regulate T cell exhaustion and ferroptosis for immunotherapy strategies

open access: yesVIEW, EarlyView.
MTV can greatly achieved antigen presenting cell (APCs), and THA will be released from the polyplex core and enhanced antigen presenting, thereby prompting APC maturation and antigen presenting. The membrane antigens on MTV are degraded into small peptides by proteasomes and presented by MHC complexes.
Anmin Huang   +9 more
wiley   +1 more source

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