Results 211 to 220 of about 72,133 (284)

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 25-55, February 2026.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology   +4 more
wiley   +1 more source

Acupuncture Alleviates Cerebral Ischemia–Reperfusion Injury by Inhibiting Ferroptosis Through the IRP2/IRE Pathway

open access: yesClinical and Experimental Pharmacology and Physiology, Volume 53, Issue 2, February 2026.
This study demonstrates that acupuncture at the Governor Vessel acupoints GV14, GV20 and GV26 alleviates neuronal death after cerebral ischemia–reperfusion injury (CIRI) by reinstating IRP2/IRE‐mediated iron homeostasis and suppressing ferroptosis. ABSTRACT Acupuncture (AC) has been demonstrated to improve outcomes in ischemic stroke.
Jia Yuan   +6 more
wiley   +1 more source

Pharmacophore‐Based Identification and Molecular Characterization of Potent Neprilysin Inhibitors: Biochemical and Therapeutic Implications for Cardiovascular Diseases

open access: yesChemical Biology &Drug Design, Volume 107, Issue 2, February 2026.
Pharmacophore‐based virtual screening and molecular dynamics identified pentagalloylglucose and tannic acid as potent, non‐toxic neprilysin inhibitors. These natural compounds demonstrated strong binding affinity and stable interactions with the catalytic Zn2+ site, offering promising leads for cardiovascular drug development. ABSTRACT Neprilysin (NEP),
Chung‐Ting Kuo   +4 more
wiley   +1 more source

Immunomodulatory Mechanism of Baiyaojian Decoction on Periodontitis: Network Pharmacology, Single‐Cell RNA Sequencing and Molecular Docking

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Periodontitis is one of the most common oral inflammatory diseases. Baiyaojian decoction, known for its prominent immunomodulatory and anti‐inflammatory properties, shows significant potential in treating periodontitis, though its molecular mechanisms remain unknown. The active ingredients and therapeutic targets were determined by integrating
Bing‐jun Chen   +5 more
wiley   +1 more source

Insights Into circRNA‐Mediated Lipid Metabolism in Cancer Progression

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Lipid metabolism reprogramming is one of the most prominent characteristics of cancer, but it is still unclear which regulatory pathways underlie this process in cancer cells. Circular RNAs (circRNAs) represent a novel category of non‐coding RNAs with multifaceted regulatory functions. While the biological roles of circRNAs in cancer have been
Zhiwei Miao   +4 more
wiley   +1 more source

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