Results 61 to 70 of about 143,679 (362)

Nursing perspective of the expert consensus on diagnosis and treatment of integrated Chinese and Western medicine in lung cancer

open access: yesJournal of Integrative Nursing, 2022
Lung cancer is a malignant tumor with the highest incidence and mortality in China, which seriously affects the quality of life of patients. Traditional Chinese medicine (TCM) plays a unique advantage in the treatment and rehabilitation of lung cancer ...
Jing Zhang   +4 more
doaj   +1 more source

Colonic Submucosa Targeted Delivery of Probiotic and Rhein for Ulcerative Colitis Treatment

open access: yesAdvanced Science, EarlyView.
A novel orally drug‐probiotic co‐delivery system designated as Rh‐YBS for UC treatment, which highlights three innovations: (i) YPs involves colonic submucosa delivery via M cells; (ii) Rh (drug) promotes the colonization and growth of BS (probiotic) in the colon.
Lingqiang Li   +21 more
wiley   +1 more source

Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome

open access: yesFrontiers in Pharmacology, 2022
Diabetic nephropathy (DN) is one of the primary complications of diabetes. Fisetin is a flavonoid polyphenol that is present in several vegetables and fruits.
Wenmin Dong   +12 more
doaj   +1 more source

The identity of a new profession: Examining the aegis of Traditional Chinese Medicine [PDF]

open access: yes, 2020
In Canada, there is a growing interest in regulating the practices of acupuncture and Chinese herbology under the banner of ‘Traditional Chinese Medicine’ (TCM). However, the origins and definition of TCM are unclear and therefore disputed.
Le, Brenda, Tellier, Darren
core   +2 more sources

Methodological Aspects of Traditional Chinese Medicine (TCM)

open access: yesAnnals of the Academy of Medicine, Singapore, 2006
The efficacy of Traditional Chinese Medicine (TCM) is less well-established than many believe and needs to be more firmly established through clinical trials. Such studies should adhere to the currently accepted standards. When planning and conducting clinical trials, one encounters numerous logistical and methodological problems.
openaire   +2 more sources

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui   +17 more
wiley   +1 more source

The potential contributions of traditional Chinese medicine to emergency medicine [PDF]

open access: yes, 2013
BACKGROUND: Despite the fact that traditional Chinese medicine (TCM) has been developed and used to treat acute and urgent illness for many thousands of years.
He, Jun, Hou, Xiang-Yu
core  

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang   +10 more
wiley   +1 more source

Intelligent Optimization of Diversified Community Prevention of COVID-19 using Traditional Chinese Medicine [PDF]

open access: yesarXiv, 2020
Traditional Chinese medicine (TCM) has played an important role in the prevention and control of the novel coronavirus pneumonia (COVID-19), and community prevention has become the most essential part in reducing the spread risk and protecting populations.
arxiv  

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

open access: yesAdvanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan   +12 more
wiley   +1 more source

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