Results 81 to 90 of about 65,860 (319)

How to protect Chinese medicine prescription more effectively?

Frontiers in Pharmacology
As an important carrier of traditional Chinese medicine (TCM) knowledge, TCM prescriptions is the crystallization of the wisdom of Chinese medical practitioners through the ages, and occupies a pivotal position in the traditional knowledge system of ...
Xiaochang Liu, Gaoyuan Zhai
doaj   +1 more source

TCM-Grid: Weaving a Medical Grid for Traditional Chinese Medicine [PDF]

, 2003
We present a TCM-Grid for Traditional Chinese Medicine (TCM). The purpose of the TCM-Grid is to aid the development of distributed systems that help health professionals, researchers, enterprizes and personal users to retrieve, integrate and share TCM information and knowledge from geographically decentralized TCM database resources and knowledge base ...
Chang Huang, Zhaohui Wu, Jiefeng Xu, Huajun Chen   +3 more
openaire   +1 more source

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

Advanced Science, EarlyView.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen, Lingyun Yue, Yanna Pan, Bingying Jiang, Junfeng Wan, Haixia Lin, Fujiang Guo, Huiyu Li, Yajuan Li, Qingjie Zhao   +9 more
wiley   +1 more source

A national survey on how to improve traditional Chinese medicine learning internationally: Perceptions from both teachers and students

Integrative Medicine Research, 2022
Background: With the increasing popularity of traditional Chinese medicine (TCM) by the global community, how to teach basic knowledge of TCM to international students and improve the teaching quality are important issues for teachers of TCM. The present
Yuhang Zhu, Yan Wu, Hao Zhang, Yanfei Zhao, Yule Ren, Wei Hu, Pan Li, Huiyi Wang, Ying Wang, Boda Zhang, Yujie Wang, Hongwen Yuan, Jiping Zhang, Wenqiang Li, Yufang Zhao, Jie Zhao, Yedong Shi, Yanye Shu, Xiao Zhang, Yan Sun, Sheng Yu, Ling Yang, Zhenbo Geng, Jiali Chen, Kun Lv, Weilin Wang, Wenjuan Xue, Yinger Gu, Fangfang Wang, Xiangrong Xu, Fan Qu   +30 more
doaj  

Relationship Between Traditional Chinese Medicine(TCM)Constitution and TCM Syndrome in the Diagnosis and Treatment of Chronic Diseases [PDF]

Chinese Medical Sciences Journal, 2018
Chronic diseases are global threats to human health. By applying the traditional Chinese medicine (TCM) theory of body constitution to the treatment of chronic diseases, and comprehensively identifying and differentiating the syndrome, disease, and constitution, TCM can be fully used in the diagnosis and treatment of chronic diseases.
Zhong-Xia Wang, Shu-Yi Liu, Rui-Lin Wang, Xiu-xiu Sang   +3 more
openaire   +2 more sources

An Ontology-Based Artificial Intelligence Model for Medicine Side-Effect Prediction: Taking Traditional Chinese Medicine as An Example [PDF]

, 2019
In this work, an ontology-based model for AI-assisted medicine side-effect (SE) prediction is developed, where three main components, including the drug model, the treatment model, and the AI-assisted prediction model, of proposed model are presented. To
Li, Liang, Liu, Runyu, Liu, Zhiyuan, Lu, Kun, Wang, Zeheng, Yan, Jing, Yao, Yuanzhe   +6 more
core   +2 more sources

ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy

Advanced Science, EarlyView.
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie, Tianyi Ji, Zixin Wan, Jie Huang, Han Li, Lingjiao Zou, Zhen Yang, Jiarui Li, Yuqi Guan, Lei Ruan, Jinhua Yan, Cuntai Zhang   +11 more
wiley   +1 more source

Integrating artificial intelligence into the modernization of traditional Chinese medicine industry: a review

Frontiers in Pharmacology
Traditional Chinese medicine (TCM) is the practical experience and summary of the Chinese nation for thousands of years. It shows great potential in treating various chronic diseases, complex diseases and major infectious diseases, and has gradually ...
E. Zhou, Qin Shen, Yang Hou
doaj   +1 more source

Novel Quaternary Ammonium Salt‐Linked STING Agonist Antibody‐Drug Conjugate: Synergistic Activation of Tumor Immunity with Mitigated Off‐Target Toxicity

Advanced Science, EarlyView.
Novel quaternary ammonium salt‐linked STING agonist ADC demonstrates high potency, stability, enhanced solubility, and reduced off‐target toxicity, potently activating the STING pathway in the tumor microenvironment through the synergistic action of the Fab and Fc regions of antibodies (activity switch‐on) while exhibiting ≈20 fold lower activity in ...
Yu Long, Borui Tang, Fei Xie, Lianqi Liu, Yangyihua Zhou, Jingwen Dong, Jianfeng Wang, Cuicui Sun, Yuting Wang, Ruoqi Li, Na Zhang, Liping Li, Longlong Luo, Junhai Xiao, Wu Zhong, Dian Xiao, Hongbin Deng, Xinbo Zhou   +17 more
wiley   +1 more source

Red Blood Cell Membrane Lipidomics: Potential Biomarkers Detecting Method for Plasma Volume Overload and Major Adverse Cardiovascular Events in Chronic Heart Failure Patients

Advanced Science, EarlyView.
A novel RBC indicator, ESI, is better than the traditional RBC indicators and is associated with CHF prevalence and in‐hospital death. RBC membrane lipidomics, Cer 18:0;O2/16:0, and LPE 18:0, are associated with plasma volume overload and MACE in CHF patients, but these plasma lipids could not.
Lin Zhang, Xiangqin Ou, Jingyi Lin, Xiaofei Luo, Jiashun Zhou, Xingyue Zhou, Peihua Zhao, Li Liu, Ziran Zhao, Ying Zhou, Guanwei Fan, Lifeng Han, Xiumei Gao   +12 more
wiley   +1 more source