Results 31 to 40 of about 10,339,775 (252)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Boundaries and Agency in Climate Uncertainty : Encountering Traditional Knowledge at the Edges of Science [PDF]

, 2008
Climate change has become an important and politicallycharged arena where traditional indigenous knowledges meet Western scientific knowledge. The positioning of Arctic science, at the edges of the scientific discourse but the centre of the climate ...
Cockburn, Lisa M.
core   +2 more sources

Mobilizing Indigenous Knowledge through the Caribou Hunter Success Working Group

Land, 2020
The caribou stewardship practices of the Iñupiat have persisted through cycles of abundance and decline for the Western Arctic Caribou Herd (WACH). This research seeks to address the challenges and opportunities faced when mobilizing Indigenous Knowledge
Hannah Atkinson
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ethnobotany of Hmong ethnic groups in Bolikhamxay province, central Laos PDR

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2023
Results from an ethnobotany study of Hmong ethnic groups in Bolikhamxay Province, Laos PDR between 2021 and 2023 identifies plant uses for 133 species, 104 genera, and 50 families. The research focusses on specific plant uses.
Kajonesuk PHENGMALA, Surapon SAENSOUK, Piyaporn SAENSOUK, Phetlasy SOULADETH   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Missing in translation: Maori language and oral tradition in scientific analyses of traditional ecological knowledge (TEK) [PDF]

, 2009
Recent conceptual shifts in ecology towards integration of humans into ecosystems requires all possible sources of ecological knowledge available (Berkes 2004, 2009 this issue).
Tom Roa, Priscilla M. Wehi, Hēmi Whaanga, Wehi, Priscilla M., Whaanga, Hēmi, Roa, Tom   +5 more
core   +1 more source

Investigating the role of edible insects on tribal health and their application for sustainable development in Odisha, India

Discover Sustainability
Most tribal and ethnic communities in India have preserved the knowledge of edible insects as a source of food and traditional medicines. Mayurbhanj being a tribal-dominated district in Odisha state, is inhabited by many tribes that find their source of ...
Debasis Nayak, Susmita Rana, Nitesh Kumar Hansdah, Arati Ho, Bibhu Prasad Panda   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Ethnomedicinal survey of the Paliyar tribe: a case study of Kadamalaikundu, Theni District

International Journal of Anthropology and Ethnology
The Paliyar tribe of Kadamalaikundu, Theni District of Tamil Nadu, India, has been deeply associated with forestry and ethnomedicinal practices for ages.
C. Divya, Monalisa Paul, Charu Lata, G. Manikandan, R. Ramasubbu   +4 more
doaj   +1 more source