Results 81 to 90 of about 5,668,692 (245)

ZNF25 as an immunotherapy target: pan-cancer biomarker potential and mechanistic exploration in glioma

open access: yesFrontiers in Oncology
BackgroundZNF25, a KRAB domain-containing zinc finger transcription factor, has been identified as a potential biomarker in ovarian cancer. However, its pan-cancer significance and the underlying molecular mechanisms in other malignancies remain largely ...
Xiaohong Yi   +11 more
doaj   +1 more source

Traditional uses, phytochemistry, and pharmacological properties of

open access: yesEuropean Journal of Inflammation, 2016
Sophora alopecuroides L. , known as ku dou zi in China, has a long history as a traditional Chinese medicine for the treatment of bacillary dysentery, enteritis, hepatitis, and other diseases, and exerts a critical role in anti-tumor.
Yan-Xia Huang   +4 more
doaj   +1 more source

A grand dame with hidden aces: The non-diabetic uses of insulin

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
This brief communication reviews the non-diabetic uses and utility of insulin. It highlights the lesser known uses in medicine, psychiatry, suregery and diagnostics that this versatile peptide has.
Asfandyar Khan Niazi   +1 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Collection and assessment of traditional medicinal plants used by the indigenous people of Dastena in Iran [PDF]

open access: yesJournal of HerbMed Pharmacology, 2016
Introduction: Nowadays, traditional and herbal medicines have attracted the attention of researchers all around the world and despite the development of synthetic drugs, demand for plant-based medicines is growing.
Habib-allah Mohammadi   +3 more
doaj  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Revolutionizing biotech and pharmaceutical education with adaptive learning

open access: yesFrontiers in Education
Adaptive learning systems (ALSs), powered by artificial intelligence (AI), represent a transformative approach to biotechnological and pharmaceutical education that addresses the critical limitations of traditional standardized pedagogy.
Tao Wang, Na Xu, Fei Liu
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Potential medicinal use of forest species of the Deciduous Seasonal Forest from Atlantic Forest Biome, South Brazil

open access: yesBrazilian Archives of Biology and Technology, 2016
The current paper focuses on potential medicinal use of forest species from Deciduous Seasonal Forest in central region of Rio Grande do Sul State, South Brazil. Floristic and phytosociological surveys were carried out in 2011 and 2012.
Ana Paula Moreira Rovedder   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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