Results 61 to 70 of about 5,668,692 (245)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
BiomoleculesBufalin is a naturally occurring bufadienolide with broad-spectrum anticancer activity. Unlike conventional cytotoxic agents, bufalin exerts pleiotropic antitumour effects by directly modulating oncogenic proteins and promoting their degradation. It also
Yanrui Yang +7 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
International Journal of Pharmaceutics: XUltraviolet (UV) radiation, particularly UVA and UVB, induces skin damage through oxidative stress and inflammation. However, existing UV protection materials fail to simultaneously block UV rays and scavenge reactive oxygen species (ROS).
Rujing Wang +9 more
doaj +1 more source
Traditional Arts Indiana Apprenticeship Program 2017-2018
, 2018 A print publication given out at the award ceremony and to the apprenticeship teams.Traditional Arts Indiana, based at Indiana University’s Mathers Museum of World Cultures, works to celebrate folk and traditional arts throughout the state, creating a ...
Traditional Arts Indiana, Kay, Jon
core
Eclipta prostrata (L.) L.: Traditional Use, Phytochemistry, and Pharmacology
, 2022 Herbs had been exploited by different cultures throughout history. In public wellness programs of the countries, drugs of natural origin play a crucial role. Eclipta prostrata (L.) L.
Al-Tawaha, A.R. +6 more
core +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Industrial Crops and ProductsDiabetic ulcers are a serious complication characterised by high rates of disability and treatment complexity, necessitating an urgent therapeutic strategy.
Siwei Xiong +15 more
doaj +1 more source
Non-traditional security perspectives on the new normal: an introduction
, 2022 What is the “new normal”, and how can Southeast Asia better prepare for and cope with it? This chapter provides an introduction to the monograph, which seeks to shed light on this overarching question, with a focus on non-traditional security (NTS ...
Montesclaros, Jose Ma. Luis P. +1 more
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source