Results 191 to 200 of about 164,752 (316)

Cancer Specific CAIX‐Targeting Supramolecular Lysosome‐Targeting Chimeras (Supra‐LYTAC) for Targeted Protein Degradation

open access: yesAdvanced Science, EarlyView.
Spatiotemporal Supra‐LYTAC formation near cancerous membrane via CAIX‐targeting is achieved. As a result of generation of Supra‐LYTAC, POI trafficking into lysosome is significantly implemented for targeted protein degradation. Abstract Recently, targeted protein degradation (TPD) strategies have emerged as a promising solution to tackle undruggable ...
Dohyun Kim   +6 more
wiley   +1 more source

Traffic engineering of management flows by link augmentations on confluent trees [PDF]

open access: green, 2005
Randeep Bhatia   +5 more
openalex   +1 more source

Inhibition of Heat Shock Protein 90β by Catalpol: A Potential Therapeutic Approach for Alleviating Inflammation‐Induced Cartilage Injuries in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
The schematic diagram delineates the chondroprotective effects of Ca‐bMSN in OA models. The upper portion of the diagram depicts the synthesis process of Ca‐bMSN. The lower section illustrates the post‐injection of Ca‐bMSN in joint cavity, catalpol released and subsequently mediates the reduction of oxidative stress, ECM catabolism, apoptosis, and ...
Zhenwei Zhou   +14 more
wiley   +1 more source

Harnessing the potential of online marketplaces in the Philippines: Insights from the National Information and Communications Technology Household Survey

open access: yesAsia &the Pacific Policy Studies, Volume 9, Issue 3, Page 288-316, September 2022., 2022
Abstract Using the Philippinesʼ first nationally representative survey designed to characterise digital commercial and non‐commercial engagements, including the use of information and communications technology (ICT), the digital economy, and technology‐enabled activities, we investigate the presence of gendered disparities in online marketplaces.
Connie Bayudan‐Dacuycuy   +1 more
wiley   +1 more source

Advances in Ovonic Threshold Switch Selector Technologies for Storage Class Memory: From Fundamentals to Development and Beyond

open access: yesAdvanced Electronic Materials, EarlyView.
This work covers ovonic threshold switches (OTSs), from basics to developments and future outlook. It explores OTS devices incorporating various chalcogens and describes how their characteristics vary by material. Engineering strategies, including elemental doping, electrode modifications, post‐treatment, and multilayer designs, are discussed ...
Sanghyun Ban   +5 more
wiley   +1 more source

The effects of extreme weather on rural transportation infrastructure and crop prices along the Lower Mississippi River

open access: yesApplied Economic Perspectives and Policy, EarlyView.
Abstract Extreme weather events are worsening the fragile rural infrastructure in the United States, impacting trade flows of agricultural products. The Mississippi River, vital for transporting agricultural commodities, reached historic lows during the 2022 and 2023 fall harvests, increasing transportation costs and lowering crop prices.
James L. Mitchell, Hunter D. Biram
wiley   +1 more source

Efficient traffic management with adaptive SDN in vehicular networks. [PDF]

open access: yesSci Rep
Rajan SJ   +8 more
europepmc   +1 more source

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