Results 241 to 250 of about 65,052 (313)

Dynamic Properties of Mineral-Based Cementitious Material-Stabilized Slurry Soil Under Vehicle Loading. [PDF]

Materials (Basel)
Sun Z, Zhao Y, Luo J, Zhou F, Ling X, Wang Y, Yang Y, Han S.   +7 more
europepmc   +1 more source

Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms

Advanced Science, EarlyView.
This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn, Soyeon Chang, Jiyoung Lee, Seok‐Ho Choi, Jinju Han, Yangsik Kim   +5 more
wiley   +1 more source

Comparative evaluation of deep learning and traditional models for predicting traffic accident severity in Saudi Arabia. [PDF]

Sci Rep
Alanazi F, Umar IK, Yosri AM, Okail MA.
europepmc   +1 more source

Stage‐Resolved Phosphoproteomic Landscape of Mouse Spermiogenesis Reveals Key Kinase Signaling in Sperm Morphogenesis

Advanced Science, EarlyView.
The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu, Yan Zhu, Xinyi Jiang, Xiangzheng Zhang, Bing Wang, Yu Chen, Yichen Zhao, Yulian Wang, Qi Zhou, Zhongyan Han, Yaling Qi, Mengjiao Luo, Haixia Tu, Bingjie Hao, Mengmeng Gao, Jie Ren, Xin Zhou, Xingyu Zhang, Xu Chen, Haojie Li, Qian Huang, Chenghao Situ, Yueshuai Guo, Hui Zhu, Yan Li, Xuejiang Guo   +25 more
wiley   +1 more source

Quantitative and qualitative changes in substance-related administrative offences in road traffic during the SARS-CoV-2 pandemic in Munich. [PDF]

PLoS One
Holzer A, Stoever A, Lau M, Gleich S, Graw M, Ludwig A, Hartung B.   +6 more
europepmc   +1 more source

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang, Yu Deng, Jianfeng Chen, Quentin Hahn, David S. Umbaugh, Zhigang Zhang, Yanqiong Zhang, Sarah E. Rowe, Lupeng Li, Laura E. Herring, Brian P. Conlon, Edward A. Miao, Blossom Damania, Anna Mae Diehl, Pengda Liu   +14 more
wiley   +1 more source

A Review of Dynamic Traffic Flow Prediction Methods for Global Energy-Efficient Route Planning. [PDF]

Sensors (Basel)
Qi P, Pan C, Xu X, Wang J, Liang J, Zhou W.   +5 more
europepmc   +1 more source

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

Advanced Science, EarlyView.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu, Wanyi Zhao, Xinyu Chen, Yanzhou Wang, Shuoshuo Wei, Bo Xiang, Yingzhou Shi, Zongyue Li, Yangyang Yao, Jin Xie, Renyuan Qiu, Meng Shu, Shuo Xu, Ping Chen, Zhiying Chen, Yingjie Wu, Weibo Xia, Ling Gao, Yongfeng Song, Jiajun Zhao, Chao Xu   +20 more
wiley   +1 more source

Dynamic road section risk identification model based on connected in-vehicle data. [PDF]

PLoS One
Zhang Y, Yang G, Xie T.
europepmc   +1 more source

Switchable Bidirectional Sound Absorption Via Exceptional Point Modulation in Acoustic Metastructures with Interleaved Resonator Coupling

Advanced Science, EarlyView.
A switchable bidirectional acoustic metastructure is proposed, enabling broadband and frequency‐selective absorption via interleaved resonator coupling and exceptional point modulation. It outperforms traditional unidirectional designs, offering compact, efficient sound control from both directions and establishing a generalized framework for extending
Zichao Guo, Liangfen Du, Zirui Yang, Kexin Zeng, Ziping Lei, Zhonggang Wang, Zhendong Li, Zheng Fan   +7 more
wiley   +1 more source