Results 41 to 50 of about 113,285 (311)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A traffic engineering system for DiffServ/MPLS networks [PDF]

open access: yes, 2003
This thesis presents an approach to traffic engineering that uses DiffServ and MPLS technologies to provide QoS guarantees over an IP network. The specific problem described here is how best to route traffic within the network such that the demands can ...
Chpenst, Alexei
core  

Planning logistics network for recyclables collection [PDF]

open access: yesYugoslav Journal of Operations Research, 2014
Rapid urbanization, intensified industrialization, rise of income, and a more sophisticated form of consumerism are leading to an increase in the amount and toxicity of waste all over the world.
Ratković Branislava   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Review of urban traffic management and the impacts of new vehicle technologies [PDF]

open access: yes, 2009
Traffic congestion is a growing problem in most urban areas across the world. In recent years, the problem has often been tackled by management of existing capacity rather than the traditional concept of more road building.
Shrestha, B.P.   +3 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Using global positioning system for bus priority in London: traffic signals close to bus stops

open access: yes, 2007
London's bus network is one of the largest and most comprehensive urban transport systems in the world. The contribution of buses is recognised by implementing a series of initiatives including bus priority at traffic signals.
Head, J. R.   +9 more
core   +1 more source

Cooperative Control of Interconnected Air Suspension Based on Energy Consumption Optimization

open access: yesShock and Vibration, 2022
In this study, a cooperative control method based on model predictive control and multiagent theory is proposed to control an interconnected air suspension system with three controllable structures of interconnection mode, damping, and vehicle height ...
Guoqing Geng   +4 more
doaj   +1 more source

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