Results 61 to 70 of about 5,389,126 (254)

The Bivariate Finite Mixture Modeling for Analyzing Freeway Correlated Crashes Under Unobserved Heterogeneity

Journal of Advanced Transportation
Unobserved heterogeneity is a key factor leading to biased estimates and unreliable crash predictions, undermining the effectiveness of safety countermeasures.
Mingjie Feng, Lulu Zhou, Jianluo Wei, Xuesong Wang, Xiaohan Yang, Jiawen Wang, Jaeyoung Jay Lee   +6 more
doaj   +1 more source

A Modified Latent Dirichlet Allocation Topic Approach for Driving Style Exploration Using Large-Scale Ride-Hailing GPS Data

Journal of Advanced Transportation, 2023
Driving style identification is of vital importance for intelligent driving system design and urban traffic management. This study aims to identify and analyze driving styles using large-scale ride-hailing GPS data taking different time periods, traffic,
Ye Li, Yiqi Chen, Jie Bao, Lu Xing, Jinjun Tang, Changyin Dong, Ruifeng Gu   +6 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Simulation study on noise reduction of electric vehicle tire with built-in sound-absorbing material

Acta Acustica
Tire cavity noise is becoming more prominent as the speed of electric vehicles is getting higher. This study aims to use a built-in sound-absorbing material to reduce tire cavity noise.
Shi Tuo, Zhou Pan, Feng Yuxin, Lv Tian, Li Yaowei, Zang Liguo   +5 more
doaj   +1 more source

Traffic engineering manual

, 2002
Title from "Main Index."; Dates vary: Cover/spine, pt. 5, 7-10, 13 last rev. 10/23/02; preface material. table of contents, pt. 1-4, 6, 11-12, 14 last rev. 01/17/03.; Harvested from the web on 2/11/03pt. 1. General -- pt. 2. Signs -- pt. 3.
Ohio.Office of Traffic Engineering
core  

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Sound absorption characteristics of honeycomb-like structure with honeycomb core direction reconstruction

Acta Acustica
To address the single shape feature and poor low- to mid-frequency sound absorption of traditional honeycomb structures, this paper proposes a honeycomb-like structure design with reconstructed core direction and diversified geometric configurations.
Feng Yuxin, Zhou Pan, Zhou Daocheng, Han Yi, Xin Jianghui, Zang Liguo   +5 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source