Results 81 to 90 of about 728,272 (252)
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Unes Journal of Swara Justisia, 2019 On the Elucidation of Law No. 22 of 2009 on Traffic and Road Transport states Education and traffic engineering is the responsibility of the Police. Some victims from laka then are children of school age.
Adhi Jais, Ebit Bimas Saputra
doaj
Review on Corrosion Mechanism and Mechanical Properties Degradation of Building Structural Steel [PDF]
E3S Web of ConferencesSteel structure is favored by many designers because of its light weight, high strength, short construction period and good seismic performance, and is widely used in high-rise, super high-rise and long-span structures, but the shortcomings of steel ...
Zhang Yixin, Zhang Shumin, Liu Kai
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Simulation study on noise reduction of electric vehicle tire with built-in sound-absorbing material
Acta AcusticaTire cavity noise is becoming more prominent as the speed of electric vehicles is getting higher. This study aims to use a built-in sound-absorbing material to reduce tire cavity noise.
Shi Tuo +5 more
doaj +1 more source
The Risk Model of Traffic Engineering Investment and Financing by Artificial Intelligence. [PDF]
Comput Intell Neurosci, 2022 Wang S, Zhang W.
europepmc +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Swarm Intelligence Internet of Vehicles Approaches for Opportunistic Data Collection and Traffic Engineering in Smart City Waste Management. [PDF]
Sensors (Basel), 2023 Ijemaru GK, Ang LM, Seng KP.
europepmc +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source