Results 51 to 60 of about 728,272 (252)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Journal of Advanced Transportation, 2023 Previous studies on pedestrian crossing have mostly focused on pedestrian crossing decisions; while as an important behavioral aspect, the pedestrian crossing process, i.e., their motions during the entire crossing process, has been narrowly studied ...
Ting Fu +6 more
doaj +1 more source
Adaptive Robust Traffic Engineering in Software Defined Networks
, 2017 One of the key advantages of Software-Defined Networks (SDN) is the opportunity to integrate traffic engineering modules able to optimize network configuration according to traffic.
Capone, Antonio +4 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Traffic engineering in ambient networks: challenges and approaches [PDF]
, 2004 The focus of this paper is on traffic engineering in ambient networks. We describe and categorize different alternatives for making the routing more adaptive to the current traffic situation and discuss the challenges that ambient networks pose on ...
Abrahamsson, Henrik, Gunnar, Anders
core +1 more source
A Primal-Dual Algorithm for Link Dependent Origin Destination Matrix Estimation
, 2016 Origin-Destination Matrix (ODM) estimation is a classical problem in transport engineering aiming to recover flows from every Origin to every Destination from measured traffic counts and a priori model information.
Abry, Patrice +6 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Planning logistics network for recyclables collection [PDF]
Yugoslav Journal of Operations Research, 2014 Rapid urbanization, intensified industrialization, rise of income, and a more sophisticated form of consumerism are leading to an increase in the amount and toxicity of waste all over the world.
Ratković Branislava +3 more
doaj +1 more source
Combined Intra- and Inter-domain Traffic Engineering using Hot-Potato Aware Link Weights Optimization [PDF]
, 2008 A well-known approach to intradomain traffic engineering consists in finding the set of link weights that minimizes a network-wide objective function for a given intradomain traffic matrix.
Balon, Simon, Leduc, Guy
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source