Results 41 to 50 of about 92,433 (265)
Flexible Traffic Signal Control via Multi-Objective Reinforcement Learning
IEEE Access, 2023 Deep reinforcement learning has been extensively studied for traffic signal control owing to its ability to process large amounts of information and achieving superior performance control.
Takumi Saiki, Sachiyo Arai
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Rekayasa SipilOne way to increase runway capacity is to set the Runway Occupancy Time Take-Off (ROTT) standard. Following the Aeronautical Information Publication of Soekarno-Hatta International Airport, the ROTT standard is set at 90 seconds.
Mohammad Ardiansyah Putra Indrawan +2 more
doaj +1 more source
A Hybrid Deep Learning Framework for Long-Term Traffic Flow Prediction
IEEE Access, 2021 An accurate and reliable traffic flow prediction is of great significance, especially the long-term traffic flow prediction e.g., 24 hours, which can help the traffic decision-makers formulate the future traffic management strategy.
Yiqun Li +3 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
World Electric Vehicle JournalThis study investigates for the first time how public charging infrastructure usage differs under the presence of diverse pricing models. About 3 million charging events from different European countries were classified according to five different ...
Markus Fischer +3 more
doaj +1 more source
Complexity, 2021 Short-term traffic flow prediction is an effective means for intelligent transportation system (ITS) to mitigate traffic congestion. However, traffic flow data with temporal features and periodic characteristics are vulnerable to weather effects, making ...
Yue Hou, Zhiyuan Deng, Hanke Cui
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source