Results 101 to 110 of about 81,822 (262)

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Long-Range Traffic Monitoring Based on Pulse-Compression Distributed Acoustic Sensing and Advanced Vehicle Tracking and Classification Algorithm. [PDF]

Sensors (Basel), 2023
Corera I, Piñeiro E, Navallas J, Sagues M, Loayssa A.   +4 more
europepmc   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

PVD: A Detection Framework for Parking Vehicles on Highways From Oblique UAV Images

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Tracking parked vehicles on highways stands as a crucial aspect of traffic monitoring. Recent developments in intelligent transportation systems have led to the utilization of unmanned aerial vehicles (UAVs) for overseeing parked vehicles using aerial ...
Junchi Bin, Jiahao Guo, Guiying Liu, Zhenhua Jiang, Mengwei Liu, Changan Yuan, Xiaoping Liu   +6 more
doaj   +1 more source

Vehicle Detection and Recognition Approach in Multi-Scale Traffic Monitoring System via Graph-Based Data Optimization. [PDF]

Sensors (Basel), 2023
Wieczorek G, Tahir SBUD, Akhter I, Kurek J.   +3 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Application of Augmented Reality in Waterway Traffic Management Using Sparse Spatiotemporal Data

Applied Sciences
The development of China’s digital waterways has led to the extensive deployment of cameras along inland waterways. However, the limited processing and utilization of digital resources hinder the ability to provide waterway services.
Ruolan Zhang, Yue Ai, Shaoxi Li, Jingfeng Hu, Jiangling Hao, Mingyang Pan   +5 more
doaj   +1 more source

Smart Railway Traffic Monitoring Using Fiber Bragg Grating Strain Gauges. [PDF]

Sensors (Basel), 2022
Van Esbeen B, Finet C, Vandebrouck R, Kinet D, Boelen K, Guyot C, Kouroussis G, Caucheteur C.   +7 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Analysis of Extended Information Provided by Bluetooth Traffic Monitoring Systems to Enhance Short-Term Level of Service Prediction. [PDF]

Sensors (Basel), 2022
Fernández Pozo R, Rodríguez González AB, Wilby MR, Vinagre Díaz JJ.   +3 more
europepmc   +1 more source