Results 11 to 20 of about 836,306 (300)

Analysis of marine conflicts [PDF]

open access: yes, 2006
The traffic conflict technique (TCT) is a powerful technique applied in road traffic safety assessment as a surrogate of the traditional accident data analysis. It has subdued the conceptual and implemental weaknesses of the accident statistics. Although
Begoña Martinez de Tejada   +7 more
core   +3 more sources

Identifying psychological and socio-economic factors affecting motorcycle helmet use [PDF]

open access: yes, 2015
Sixty percent of motorcyclist fatalities in traffic accidents of Iran are due to head injuries, but helmet use is low, despite it being a legal requirement.
Groeger, John A.   +2 more
core   +1 more source

Integrating driving and traffic simulators for the study of railway level crossing safety interventions: a methodology [PDF]

open access: yes, 2012
Safety at Railway Level Crossings (RLXs) is an important issue within the Australian transport system. Crashes at RLXs involving road vehicles in Australia are estimated to cost $10 million each year.
Ferreira, Luis   +4 more
core   +2 more sources

Generating Comfortable, Safe and Comprehensible Trajectories for Automated Vehicles in Mixed Traffic

open access: yes, 2018
While motion planning approaches for automated driving often focus on safety and mathematical optimality with respect to technical parameters, they barely consider convenience, perceived safety for the passenger and comprehensibility for other traffic ...
Lauer, Martin   +2 more
core   +1 more source

Design and Preliminary Testing of Demand-Responsive Transverse Rumble Strips [PDF]

open access: yes, 2019
Transverse rumble strips are common practice to alert drivers by engaging their auditory and tactile senses in addition to visual senses by traffic signals.
Hossen, Md Shakhawat   +5 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

VisionSense - An advanced lateral collision warning system [PDF]

open access: yes, 2005
VisionSense is an advanced driver assistance system which combines a lateral collision warning system with vehicle-to-vehicle communication. This paper shows the results of user needs assessment and traffic safety modelling of VisionSense.
Dijck, T., Heijden, G.A.J. van der
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Enabling Data-Driven Transportation Safety Improvements in Rural Alaska [PDF]

open access: yes, 2019
Safety improvements require funding. A clear need must be demonstrated to secure funding. For transportation safety, data, especially data about past crashes, is the usual method of demonstrating need.
Bennett, F. Lawrence   +2 more
core  

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