Results 21 to 30 of about 836,306 (300)

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

The effects of alcohol on driver performance in a decision making situation [PDF]

open access: yes, 1978
The results are reviewed of driving simulator and in-vehicle field test experiments of alcohol effects on driver risk taking. The objective was to investigate changes in risk taking under alcoholic intoxication and relate these changes to effects on ...
Allen, R. W.   +3 more
core   +1 more source

Improving Traffic Safety Through Video Analysis in Jakarta, Indonesia

open access: yes, 2018
This project presents the results of a partnership between the Data Science for Social Good fellowship, Jakarta Smart City and Pulse Lab Jakarta to create a video analysis pipeline for the purpose of improving traffic safety in Jakarta.
Caldeira, João   +10 more
core   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Air Traffic Safety: continued evolution or a new Paradigm. [PDF]

open access: yes, 2007
The context here is Transport Risk Management. Is the philosophy of Air Traffic Safety different from other modes of transport? – yes, in many ways, it is.
Brooker, Peter
core  

Cost-effectiveness of traffic enforcement: case study from Uganda [PDF]

open access: yes, 2008
BACKGROUND: In October 2004, the Ugandan Police department deployed enhanced traffic safety patrols on the four major roads to the capital Kampala. OBJECTIVE: To assess the costs and potential effectiveness of increasing traffic enforcement in Uganda.
Abbas, Syed Shahid   +4 more
core   +1 more source

Ice Lithography: Recent Progress Opens a New Frontier of Opportunities

open access: yesAdvanced Functional Materials, EarlyView.
This review focuses on recent advancements in ice lithography, including breakthroughs in compatible precursors and substrates, processes and applications, hardware, and digital methods. Moreover, it offers a roadmap to uncover innovation opportunities for ice lithography in fields such as biological, nanoengineering and microsystems, biophysics and ...
Bingdong Chang   +9 more
wiley   +1 more source

Risk management for traffic safety control [PDF]

open access: yes, 2002
This paper offers a range of modelling ideas and techniques from mathematical statistics appropriate for analysing traffic accident data for the East region operation of CLP Power Hong Kong Limited and for the Hong Kong population in general.
Luczak, M.J., Wylie, J.
core  

Detecting Traffic Conditions Model Based On Clustering Nodes Situations In VANET [PDF]

open access: yes, 2015
In the last decade, cooperative vehicular network has been one of the most studied areas for developing the intelligent transportation systems (ITS).
Abufanas, A, Peytchev, E
core   +1 more source

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