Results 41 to 50 of about 78,818 (264)

Stability Analysis and Prediction of Traffic Flow of Trucks at Road Intersections Based on Heterogenous Optimal Velocity and Artificial Neural Network Model

open access: yesSmart Cities, 2022
The evolution of traffic-related accidents caused by long, short, and medium trucks at signalized road intersections have been underemphasized in the last few years.
Isaac Oyeyemi Olayode   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Health Risk of Increased O3 Concentration Based on Regional Emission Characteristics under the Unusual State of the COVID-19 Pandemic

open access: yesAtmosphere, 2021
Photochemical oxidant concentration increases with the decrease in nitrogen oxide (NOx) concentration in volatile organic compound (VOC)-sensitive areas with several automobiles and factories.
Yuki Okazaki, Lisa Ito, Akihiro Tokai
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

On the Distribution of Traffic Volumes in the Internet and its Implications [PDF]

open access: yesIEEE INFOCOM 2019 - IEEE Conference on Computer Communications, 2019
Accepted for INFOCOM ...
Mohammed Alasmar   +3 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

The Effect of Road Traffic Noise at Hospitals in Baghdad City

open access: yesJournal of Engineering and Sustainable Development, 2014
Noise is a prominent feature of the environment.of all the sources of noise pollution, road traffic is the most prevalent and perhaps damaging source of noise pollution.
Zeena T. Jaleel
doaj  

Induced Traffic Volume Prediction of a New Highway Based on the ESE Gravity Model

open access: yesJournal of Advanced Transportation
Induced traffic volume is an important indicator for evaluating the feasibility of traffic project construction and predicting traffic demand. However, among the many models used in engineering to predict induced traffic volume, the economic spillover ...
Yifan Li, Mengmeng Zhang
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

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