Results 101 to 110 of about 968,579 (338)

Design, Analysis and Control of Tracked Mobile Robot with Passive Suspension on Rugged Terrain

Actuators
With the application of tracked mobile robots in detection and rescue, how to improve their stability and trafficability has become the research focus. In order to improve the driving ability and trafficability of tracked mobile robots in rugged terrain,
Junfeng Gao, Yi Li, Jingfu Jin, Zhicheng Jia, Chao Wei   +4 more
doaj   +1 more source

Material studies related to lunar surface exploration, volume 3 Final report, 6 Mar. 1967 - 30 Jun. 1968 [PDF]

Mechanical properties of lunar soils related to lunar ...
Carmichael, I. C., Frisch, J., Goodman, R. E., Heuze, F. E., Mitchell, J. K., Witherspoon, P. A.   +5 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Four-wheel Steering Control Algorithm of Long Wheelbase Vehicles

Kongzhi Yu Xinxi Jishu
Long wheelbase design of vehicle can effectively increase the standing area without increasing the body length, thus increasing the passenger capacity. Today, with the development of urbanization, the long wheelbase vehicle design has become a trend, but
ZHONG Hanwen, XIAO Lei, CHEN Wenguang, BU Jiling, LIU Biao   +4 more
doaj   +3 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Lunar surface engineering properties experiment definition Quarterly report, 1 Oct. - 31 Dec. 1968 [PDF]

Mechanical properties of simulated lunar ...
Goodman, R. E., Houston, W. N., Mitchell, J. K., Witherspoon, P. A.   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Application of Sofia Plus catheter tip shaping in the treatment of acute middle cerebral artery occlusion: A case control study. [PDF]

Medicine (Baltimore), 2023
Han N, Ma L, Xie Y, Xu G, Jia Y, Zhang N, Wang H.   +6 more
europepmc   +1 more source

Evaluation of geophysical properties of the lunar regolith for the design of precursor scientific missions for the space exploration initiative [PDF]

The following topics are addressed: (1) the frequency of encountering boulders that represent hazards to lunar operations; (2) the ease of lunar soil excavation; (3) the use of explosives in excavation operation; (4) the trafficability of the regolith ...
Morgan, Paul
core   +1 more source