Results 51 to 60 of about 1,719 (293)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Evaluating vehicle trafficability on soft ground using wheel force information
Measurement + ControlIn the areas of aerospace and military industry, wheeled vehicles are expected to have the ability of passing various ground surfaces, including lunar soil, sand, marsh, mud flat, etc.
Mingming Liu, Longlong Chen, Yanxi Ren
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Trafficability of soils: Analysis of existing data
, 2020 no . 3-2'40 Sup. c .' TRAFFICABILITY OF SOILS ANALYSIS OF EXISTING DATA RESTRICTED TECHNICAL MEMORANDUM NO. 3-240 FIFTH SUPPLEMENT WATERWAYS EXPERIMEVNT STATION VICKSDURG, MISSISSIPPI MAY 1949 CORPS OF ENGINEERS, U. S.
Waterways Experiment Station (U.S.); United States. Mississippi River Commission;
core
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Impact Assessing of Traffic Lights via GPS Vehicle Trajectories
ISPRS International Journal of Geo-Information, 2021 The adaptability of traffic lights in the control of vehicle traffic heavily affects the trafficability of vehicles and the travel efficiency of traffic participants in busy urban areas.
Zhuhua Liao +4 more
doaj +1 more source
Simulation Analysis and Test of Trafficability on Forest Patrolling and Fire-Fighting Vehicle
, 2010 Forest safety and the application of virtual prototyping technology were investigated. Forest patrolling and fire-fighting vehicle was surveyed and mapped.
Xing Qiang Ba +2 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source