Results 11 to 20 of about 904,971 (330)
Deep and fast label-free Dynamic Organellar Mapping
Nature Communications, 2023 The Dynamic Organellar Maps (DOMs) approach combines cell fractionation and shotgun-proteomics for global profiling analysis of protein subcellular localization.
Julia P. Schessner +4 more
doaj +1 more source
AMA Journal of Ethics, 2018 This first-person narrative describes some of the barriers to caring well for patients at the intersection of human trafficking and substance use disorder. I canvass some of the ethical considerations regarding these patients' autonomy and call for establishing and using evidence-based practice to manage these complex scenarios.
openaire +2 more sources
Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of genetic risk factors
Molecular Neurodegeneration, 2019 Increasing evidence supports that cellular dysregulations in the degradative routes contribute to the initiation and progression of neurodegenerative diseases, including Alzheimer’s disease.
Zoë P. Van Acker +2 more
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VAMP5 and distinct sets of cognate Q-SNAREs mediate exosome release
Cell Structure and Function, 2023 Small extracellular vesicles (sEVs) are largely classified into two types, plasma-membrane derived sEVs and endomembrane-derived sEVs. The latter type (referred to as exosomes herein) is originated from late endosomes or multivesicular bodies (MVBs).
Takahide Matsui +3 more
doaj +1 more source
Molecular mechanisms of endomembrane trafficking in plants.
The Plant Cell, 2021 Endomembrane trafficking is essential for all eukaryotic cells. The best-characterized membrane trafficking organelles include the endoplasmic reticulum (ER), Golgi apparatus, early and recycling endosomes, multivesicular body (MVB) or late endosome (LE),
F. Aniento +4 more
semanticscholar +1 more source
Retrovirology, 2018 Background The ability of human immunodeficiency virus type 1 (HIV-1) to form a stable viral reservoir is the major obstacle to an HIV-1 cure and post-transcriptional events contribute to the maintenance of viral latency.
Shringar Rao +4 more
doaj +1 more source
Pathologies of Security Governance: Efforts Against Human Trafficking in Europe [PDF]
, 2007 The trafficking of women and girls for the purpose of sexual exploitation has reportedly been booming in Europe since the 1990s. Governments, international organizations, and private actors have addressed the causes and consequences of sex trafficking in
Friesendorf, Cornelius
core +1 more source
Contrasting the conceptualisation of victims of trafficking for sexual exploitation: a case study of Brazilians in Spain and Portugal [PDF]
, 2014 Despite the significant emphasis given to the trafficking of Brazilians to the sex industry of the Iberian Peninsula, the concepts of “victim of trafficking for sexual exploitation” used in these three countries vary.
Lima De Perez, Julie
core +1 more source
Autophagy Induction via STING Trafficking Is a Primordial Function of the cGAS Pathway
Nature, 2019 Cyclic GMP-AMP (cGAMP) synthase (cGAS) detects infections or tissue damage by binding to microbial or self DNA in the cytoplasm1. Upon binding DNA, cGAS produces cGAMP that binds to and activates the adaptor protein STING, which then activates the ...
Xiang Gui +7 more
semanticscholar +1 more source
Asian Journal of Law and Policy, 2022 Maritime delimitation, which ensures the jurisdiction exertion and effective use of maritime spaces of coastal States, never involves minimal efforts.
Quyen Mai Nguyen, Linh Thao Nguyen
doaj +1 more source